Projects per year
Organization profile
Organization profile
The PhD program in Cell Biology and Biomedicine trains researchers capable of contributing to the knowledge about the normal and pathological functioning of the cell, and apply this knowledge to understand and control diseases that require better treatments or lack of treatment.
It addresses in a multidisciplinary manner the interrelationships between cellular organization, structure and function, their dynamic interactions with the environment, their integration into the physiology of the organism and their alterations leading to disease as a rational for the search of innovative therapeutic alternatives.
The PhD program in Cell Biology and Biomedicine includes integrated and interactive courses, specialized laboratory practices, research units and development of an experimental thesis.
It trains in the use of advanced techniques in Cell Biology, Molecular Biology and Structural Biology (microinjection, state-of-the-art spectral confocal microscopy, live cell fluorescence microscopy, gene editing, structural bioinformatics).
It integrates the student to a wide network of collaborations and exchange opportunities with laboratories of prestigious national and international institutions.
The PhD is organized around the following lines of research, corresponding to the areas of Cell Biology and Biomedicine, which include aspects based on structural biology and molecular biology and are addressed through the research topics and associated research projects.
The cellular processes included in these topics are dealt with by addressing their mechanisms and functions, as well as their alterations as a cause of disease and as a rationale for searching for new therapeutic targets, incorporating potential selective therapeutic targets according to structural bioinformatics. The aim is to provide treatments that have a positive impact on people's health and quality of life.
The program has three lines of research:
- Protein and membrane trafficking: mechanisms, functions and disease
- Pathologies associated with autoantibodies, inflammation, metabolism and/or aging
- Homeostasis, recycling and cellular plasticity: mechanisms and disease
Organization profile
The PhD program in Cell Biology and Biomedicine trains researchers capable of contributing to the knowledge about the normal and pathological functioning of the cell, and apply this knowledge to understand and control diseases that require better treatments or lack of treatment.
It addresses in a multidisciplinary manner the interrelationships between cellular organization, structure and function, their dynamic interactions with the environment, their integration into the physiology of the organism and their alterations leading to disease as a rational for the search of innovative therapeutic alternatives.
The PhD program in Cell Biology and Biomedicine includes integrated and interactive courses, specialized laboratory practices, research units and development of an experimental thesis.
It trains in the use of advanced techniques in Cell Biology, Molecular Biology and Structural Biology (microinjection, state-of-the-art spectral confocal microscopy, live cell fluorescence microscopy, gene editing, structural bioinformatics).
It integrates the student to a wide network of collaborations and exchange opportunities with laboratories of prestigious national and international institutions.
The PhD is organized around the following lines of research, corresponding to the areas of Cell Biology and Biomedicine, which include aspects based on structural biology and molecular biology and are addressed through the research topics and associated research projects.
The cellular processes included in these topics are dealt with by addressing their mechanisms and functions, as well as their alterations as a cause of disease and as a rationale for searching for new therapeutic targets, incorporating potential selective therapeutic targets according to structural bioinformatics. The aim is to provide treatments that have a positive impact on people's health and quality of life.
The program has three lines of research:
- Protein and membrane trafficking: mechanisms, functions and disease
- Pathologies associated with autoantibodies, inflammation, metabolism and/or aging
- Homeostasis, recycling and cellular plasticity: mechanisms and disease
Fingerprint
Collaborations and top research areas from the last five years
Profiles
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Carolina Del Carmen Añazco Oyarzún, PhD
- Universidad San Sebastián - Investigador
- Facultad de Ciencias de la Rehabilitación y Calidad de Vida - Investigador
- Sede Valdivia - Investigador
- Magíster en Biomedicina Molecular - Investigador
- Doctorado en Enfermedades Crónicas - Investigador
- Doctorado en Biología Celular y Biomedicina - Investigador
Person: Researcher
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Raul René Araya Secchi, PhD
- Universidad San Sebastián - Investigador
- Facultad de Ingeniería - Investigador
- Sede Santiago - Investigador
- Magíster en Biomedicina Molecular - Investigador
- Doctorado en Ingeniería - Investigador
- Doctorado en Biología Computacional - Investigador
- Doctorado en Biología Celular y Biomedicina - Investigador
Person: Researcher
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María José Barrera Alvarado, PhD
- Universidad San Sebastián - Investigador
- Facultad de Odontología - Investigador
- Sede Santiago - Investigador
- Magíster en Biomedicina Molecular - Investigador
- Doctorado en Enfermedades Crónicas - Investigador
- Doctorado en Biología Celular y Biomedicina - Investigador
Person: Researcher
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FONDECYT E-13240033: Primary Cilium-Derived Ectosomes: A Novel Mechanism for the Control of Inflammation in the Hypothalamus
Morselli, E. (Investigador(a) Responsable), Varas Godoy, M. A. (Deputy director) & Criollo, A. (CoI)
03/11/24 → 02/11/28
Project: PROYECTO DE INVESTIGACIÓN
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FONDECYT R-1241526: Pro-inflammatory cytokines decrease unsaturated cardiolipin levels and/or mitophagy, promoting mitochondrial damage and its extracellular release in salivary epithelial cells of Sjögren’s syndrome patients.
Barrera Alvarado, M. J. (Investigador(a) Responsable), Providell, S. G. (CoI), Aguilera Covarrubias, S. O. (CoI), González Burgos, M. J. (CoI) & Molina Castillo, C. T. (CoI)
Agencia Nacional de Investigaci?n y Desarrollo
01/04/24 → 31/03/28
Project: PROYECTO DE INVESTIGACIÓN
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FONDECYT R-1240623: The Primary Cilium-Mitophagy Axis in AgRP Neurons: Role in the Control of Food Intake and Body Weight
Morselli, E. (Investigador(a) Responsable), Criollo, A. (CoI) & Parra, V. (CoI)
Agencia Nacional de Investigaci?n y Desarrollo
01/04/24 → 31/03/28
Project: PROYECTO DE INVESTIGACIÓN
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A complex multisystem disorder including hypopituitarism and hypoparathyroidism, associated with mutation in the gene encoding fatty acid synthase (FASN)
Gregory, L. C., Krywawych, S., Rahman, S., Lagos, C. F., Eaton, S. & Dattani, M. T., 2025, In: Metabolism. 168, 156256.Research output: Contribution to journal › Article › peer-review
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Ageing-related changes in the regulation of microglia and their interaction with neurons
von Bernhardi, R. & Eugenín, J., 2025, In: Neuropharmacology. 265, p. 1-21 21 p., 110241.Research output: Contribution to journal › Article › peer-review
1 Scopus citations -
A primary cilia–autophagy axis in hippocampal neurons is essential to maintain cognitive resilience
Rivagorda, M., Romeo-Guitart, D., Blanchet, V., Mailliet, F., Boitez, V., Barry, N., Milunov, D., Siopi, E., Goudin, N., Moriceau, S., Guerrera, C., Leibovici, M., Saha, S., Codogno, P., Morselli, E., Morel, E., Armand, A. S. & Oury, F., 2025, In: Nature Aging. 5, 3, p. 450-467 18 p., 1318.Research output: Contribution to journal › Article › peer-review
Open Access4 Scopus citations
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Neuroendocrine Techniques at the Cutting Edge
Kerr Fuentes, B. D. (Organizer), Belsham, D. (Organizer), Lehman, M. (Organizer), Marshall, C. (Organizer), Evans, N. (Organizer) & Navarro, V. (Organizer)
2023 → 2023Activity: Participating in or organizing an event › Organizing a conference, workshop, ...
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Neuroendocrine Integration of Appetite and Metabolism
Kerr Fuentes, B. D. (Organizer), Navarro, V. (Participant), Scherer, P. E. (Participant), Matus Montero, M. S. (Participant) & Lee Liu, D. N. (Participant)
2023 → 2023Activity: Participating in or organizing an event › Participating in a conference, workshop, ...
Press/Media
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Discutiendo el futuro de la biología: Dr. Roberto Mayor visita la USS
26/03/24
1 Media contribution
Press/Media
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Descentralizando la ciencia: Doctorado en Biología Celular y Biomedicina USS llega a sede Valdivia
25/03/24
2 Media contributions
Press/Media
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Colaboración y nuevos horizontes para la salud y la enfermedad en Science & Friendship 2023
22/11/23
1 Media contribution
Press/Media
Equipment
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Analizador de Imágenes Luminiscentes
Gutiérrez Pérez, J. A. (Manager), Leiva Mendoza, A. A. (Manager), Barrera Alvarado, M. J. (Manager), Contreras Duarte, S. D. L. M. (Manager), Yáñez Henríquez, M. J. (Manager), Morselli, E. (Manager), Chiarello Peñaranda, D. (Manager), Carrasco Wong, I. J. (Manager), Lagos Arevalo, C. F. (Manager), Amador Carrasco, C. A. (Manager) & Vio Lagos, C. (Manager)
Equipment/facility: Equipment
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Autoclave
Lagos Arevalo, C. F. (Operator), Chiarello Peñaranda, D. (Operator), Amador Carrasco, C. A. (Operator), Carrasco Wong, I. J. (Operator), Morselli, E. (Operator), Leiva Mendoza, A. A. (Operator), Barrera Alvarado, M. J. (Operator), Contreras Duarte, S. D. L. M. (Operator), Gutiérrez Pérez, J. A. (Operator), Yáñez Henríquez, M. J. (Operator), Soto Arriaza, M. A. (Operator) & Lee Liu, D. N. (Manager)
Equipment/facility: Equipment
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Campana de Extracción de Gases
Gutiérrez Pérez, J. A. (Operator), Leiva Mendoza, A. A. (Operator), Barrera Alvarado, M. J. (Operator), Contreras Duarte, S. D. L. M. (Operator), Carrasco Wong, I. J. (Operator), Yáñez Henríquez, M. J. (Operator), Soto Arriaza, M. A. (Operator), Chiarello Peñaranda, D. (Operator), Amador Carrasco, C. A. (Operator), Morselli, E. (Operator), Lagos Arevalo, C. F. (Operator), Lee Liu, D. N. (Operator) & Vio Lagos, C. (Manager)
Equipment/facility: Equipment