TY - JOUR
T1 - Synthesis of Surfactant-Modified Poly (Acrylamide-co-Potassium Acrylate) Hydrogels and Its in vitro Release Studies
AU - Ravindra, Sakey
AU - Mulaba-Bafubiandi, Antoine F.
AU - Rajineekanth, Vanarchi
AU - Varaprasad, Kokkarachedu
AU - Raju, Konduru Mohana
N1 - Funding Information:
The authors (SR and KMR) thanks the University Grants Commission (UGC-SAP), Government of India, New Delhi for the partial financial support and AFM thanks the University of Johannesburg, South Africa for the partial financial support.
PY - 2012/9
Y1 - 2012/9
N2 - In present investigation, a series of hydrogels, composed with Surfactant and poly(Acrylamide-co-Potassium acrylate), using Ammonium per sulfate(APS)/N,N,N 1, N 1-tetram ethylethylene diamine (TMEDA) initiating system and N,N 1-methylenebisacrlyamide (MBA) as crosslinker. The prepared hydrogel was characterized by using Fourier transform infrared spectroscopy (FTIR), Thermo gravimetric analysis (TGA), Scanning electron microscopy (SEM). The controlled release characteristics of the matrices for Triprolidene hydrochloride (TH) were investigated in pH 7.4 media. Drug was released in a controlled manner up to 1400 min.
AB - In present investigation, a series of hydrogels, composed with Surfactant and poly(Acrylamide-co-Potassium acrylate), using Ammonium per sulfate(APS)/N,N,N 1, N 1-tetram ethylethylene diamine (TMEDA) initiating system and N,N 1-methylenebisacrlyamide (MBA) as crosslinker. The prepared hydrogel was characterized by using Fourier transform infrared spectroscopy (FTIR), Thermo gravimetric analysis (TGA), Scanning electron microscopy (SEM). The controlled release characteristics of the matrices for Triprolidene hydrochloride (TH) were investigated in pH 7.4 media. Drug was released in a controlled manner up to 1400 min.
KW - Drug release
KW - Hydrogel
KW - Surfactant
UR - http://www.scopus.com/inward/record.url?scp=84867226929&partnerID=8YFLogxK
U2 - 10.1080/03602559.2012.702255
DO - 10.1080/03602559.2012.702255
M3 - Article
AN - SCOPUS:84867226929
SN - 0360-2559
VL - 51
SP - 1355
EP - 1360
JO - Polymer - Plastics Technology and Engineering
JF - Polymer - Plastics Technology and Engineering
IS - 13
ER -