@article{a25beac39f214f82ae8e9f69cc97fd1e,
title = "PAD2-Mediated Citrullination Contributes to Efficient Oligodendrocyte Differentiation and Myelination",
abstract = "Falc{\~a}o et al. demonstrate that PAD2-mediated citrullination, the conversion of peptidylarginine into peptidylcitrulline, has two roles in oligodendrocyte cells. In the nucleus, PAD2 acts as a chromatin modifier contributing to efficient oligodendrocyte precursor cell differentiation, while in the cytoplasm PAD2 is required for proper oligodendrocyte myelination.",
keywords = "PAD2, Padi2, SILAC, chromatin accessibility, citrullination, deamination, multiple sclerosis, myelin, oligodendrocytes, proteomics",
author = "Falc{\~a}o, {Ana Mendanha} and Mandy Meijer and Antonella Scaglione and Puneet Rinwa and Eneritz Agirre and Jialiang Liang and Larsen, {Sara C.} and Abeer Heskol and Rebecca Frawley and Michael Klingener and Manuel Varas-Godoy and Raposo, {Alexandre A.S.F.} and Patrik Ernfors and Castro, {Diogo S.} and Nielsen, {Michael L.} and Patrizia Casaccia and Gon{\c c}alo Castelo-Branco",
note = "Publisher Copyright: {\textcopyright} 2019 The Authors",
year = "2019",
month = apr,
day = "23",
doi = "10.1016/j.celrep.2019.03.108",
language = "English",
volume = "27",
pages = "1090--1102.e10",
journal = "Cell Reports",
issn = "2211-1247",
publisher = "Cell Press",
number = "4",
}