HIV/SIV-Nef: Pas de trois Choreographies to Evade Immunity

Luis L.P. daSilva; Gonzalo A. Mardones

doi:10.1016/j.tim.2018.09.003

HIV/SIV-Nef: Pas de trois Choreographies to Evade Immunity

Luis L.P. daSilva^*, Gonzalo A. Mardones

^*Autor correspondiente de este trabajo

Producción científica: Contribución a una revista › Estudio breve › revisión exhaustiva

3 Citas (Scopus)

Resumen

Nef is a major pathogenic factor of human and simian immunodeficiency viruses that hijacks protein trafficking through physical interaction with vesicle coats. This alters the subcellular localization of proteins involved in immunity and neutralizes their function. Understanding the structural bases for these interactions could reveal new targets for antiviral intervention.

Idioma original	Inglés
Páginas (desde-hasta)	889-891
Número de páginas	3
Publicación	Trends in Microbiology
Volumen	26
N.º	11
DOI	https://doi.org/10.1016/j.tim.2018.09.003
Estado	Publicada - 2018

Nota bibliográfica

Publisher Copyright:
© 2018 Elsevier Ltd

Áreas temáticas de ASJC Scopus

Microbiología
Microbiología (médica)
Virología
Enfermedades infecciosas

ODS de las Naciones Unidas

Este resultado contribuye a los siguientes Objetivos de Desarrollo Sostenible

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10.1016/j.tim.2018.09.003

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title = "HIV/SIV-Nef: Pas de trois Choreographies to Evade Immunity",

abstract = "Nef is a major pathogenic factor of human and simian immunodeficiency viruses that hijacks protein trafficking through physical interaction with vesicle coats. This alters the subcellular localization of proteins involved in immunity and neutralizes their function. Understanding the structural bases for these interactions could reveal new targets for antiviral intervention.",

keywords = "AP-1, HIV, MHC-I, Nef, SIV, tetherin",

author = "daSilva, {Luis L.P.} and Mardones, {Gonzalo A.}",

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AU - Mardones, Gonzalo A.

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KW - AP-1

KW - HIV

KW - MHC-I

KW - Nef

KW - SIV

KW - tetherin

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M3 - Short survey

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ER -

HIV/SIV-Nef: Pas de trois Choreographies to Evade Immunity

Resumen

Nota bibliográfica

Áreas temáticas de ASJC Scopus

ODS de las Naciones Unidas

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