Dioxin-like compounds bioavailability and genotoxicity assessment in the Gulf of Follonica, Tuscany (Northern Tyrrhenian Sea)

Patrizia Guidi, Simonetta Corsolini, Margherita Bernardeschi, Lucia Rocco, Marco Nigro*, Davide Baroni, Filomena Mottola, Vittoria Scarcelli, Marianna Santonastaso, Alessandra Falleni, Camilla Della Torre, Ilaria Corsi, Karla Pozo, Giada Frenzilli

*Autor correspondiente de este trabajo

Producción científica: Contribución a una revistaArtículorevisión exhaustiva

5 Citas (Scopus)

Resumen

The Gulf of Follonica (Italy) is impacted by the chemical pollution from ancient mining activity and present industrial processes. This study was aimed to determine the bioavailability of dioxin-like compounds (DLCs) in coastal marine environment and to assess the genotoxic potential of waste waters entering the sea from an industrial canal. Moderately high levels of DCLs compounds (∑ PCDDs + PCDFs 2.18–29.00 pg/g dry wt) were detected in Mytilus galloprovincialis transplanted near the waste waters canal and their corresponding Toxic Equivalents (TEQs) calculated. In situ exposed mussels did not show any genotoxic effect (by Comet and Micronucleus assay). Otherwise, laboratory exposure to canal waters exhibited a reduced genomic template stability (by RAPD-PCR assay) but not DNA or chromosomal damage. Our data reveal the need to focus on the levels and distribution of DLCs in edible species from the study area considering their potential transfer to humans through the consumption of sea food.

Idioma originalInglés
Páginas (desde-hasta)467-472
Número de páginas6
PublicaciónMarine Pollution Bulletin
Volumen126
DOI
EstadoPublicada - 2018
Publicado de forma externa

Nota bibliográfica

Publisher Copyright:
© 2017 Elsevier Ltd

Áreas temáticas de ASJC Scopus

  • Oceanografía
  • Ciencias acuáticas
  • Contaminación

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