Association between adiposity levels and cognitive impairment in the Chilean older adult population

Y. Concha-Cisternas; F. Lanuza; H. Waddell; Anne Sillars; A. M. Leiva; C. Troncoso; M. A. Martinez; M. Villagrán; L. Mardones; M. Martorell; G. Nazar; N. Ulloa; A. M. Labraña; X. Diaz-Martinez; K. Sadarangani; C. Alvarez; R. Ramirez-Campillo; Alex Garrido-Mendez; Cristian Luarte; Frederick Ho; Stuart R. Gray; F. Petermann-Rocha; C. Celis-Morales

doi:10.1017/jns.2019.24

Association between adiposity levels and cognitive impairment in the Chilean older adult population

Y. Concha-Cisternas, F. Lanuza, H. Waddell, Anne Sillars, A. M. Leiva, C. Troncoso, M. A. Martinez, M. Villagrán, L. Mardones, M. Martorell, G. Nazar, N. Ulloa, A. M. Labraña, X. Diaz-Martinez, K. Sadarangani, C. Alvarez, R. Ramirez-Campillo, Alex Garrido-Mendez, Cristian Luarte, Frederick HoStuart R. Gray, F. Petermann-Rocha, C. Celis-Morales^*

^*Autor correspondiente de este trabajo

Producción científica: Contribución a una revista › Artículo › revisión exhaustiva

12 Citas (Scopus)

Resumen

Although both obesity and ageing are risk factors for cognitive impairment, there is no evidence in Chile on how obesity levels are associated with cognitive function. Therefore, the aim of the present study was to investigate the association between adiposity levels and cognitive impairment in older Chilean adults. This cross-sectional study includes 1384 participants, over 60 years of age, from the Chilean National Health Survey 2009-2010. Cognitive impairment was evaluated using the Mini-Mental State Examination. BMI and waist circumference (WC) were used as measures of adiposity. Compared with people with a normal BMI, the odds of cognitive impairment were higher in participants who were underweight (OR 4·44; 95 % CI 2·43, 6·45; P < 0·0001), overweight (OR 1·86; 95 % CI 1·06, 2·66; P = 0·031) and obese (OR 2·26; 95 % CI 1·31, 3·21; P = 0·003). The associations were robust after adjustment for confounding variables. Similar results were observed for WC. Low and high levels of adiposity are associated with an increased likelihood of cognitive impairment in older adults in Chile.

Idioma original	Inglés
Número de artículo	e33
Publicación	Journal of Nutritional Science
Volumen	8
DOI	https://doi.org/10.1017/jns.2019.24
Estado	Aceptada/en prensa - 2019

Nota bibliográfica

Publisher Copyright:
Copyright © The Author(s) 2019 This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.

Áreas temáticas de ASJC Scopus

Alimentación
Endocrinología, diabetes y metabolismo
Nutrición y dietética

ODS de las Naciones Unidas

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Concha-Cisternas, Y., Lanuza, F., Waddell, H., Sillars, A., Leiva, A. M., Troncoso, C., Martinez, M. A., Villagrán, M., Mardones, L., Martorell, M., Nazar, G., Ulloa, N., Labraña, A. M., Diaz-Martinez, X., Sadarangani, K., Alvarez, C., Ramirez-Campillo, R., Garrido-Mendez, A., Luarte, C., ... Celis-Morales, C. (Aceptado/En prensa). Association between adiposity levels and cognitive impairment in the Chilean older adult population. Journal of Nutritional Science, 8, Artículo e33. https://doi.org/10.1017/jns.2019.24

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title = "Association between adiposity levels and cognitive impairment in the Chilean older adult population",

abstract = "Although both obesity and ageing are risk factors for cognitive impairment, there is no evidence in Chile on how obesity levels are associated with cognitive function. Therefore, the aim of the present study was to investigate the association between adiposity levels and cognitive impairment in older Chilean adults. This cross-sectional study includes 1384 participants, over 60 years of age, from the Chilean National Health Survey 2009-2010. Cognitive impairment was evaluated using the Mini-Mental State Examination. BMI and waist circumference (WC) were used as measures of adiposity. Compared with people with a normal BMI, the odds of cognitive impairment were higher in participants who were underweight (OR 4·44; 95 % CI 2·43, 6·45; P < 0·0001), overweight (OR 1·86; 95 % CI 1·06, 2·66; P = 0·031) and obese (OR 2·26; 95 % CI 1·31, 3·21; P = 0·003). The associations were robust after adjustment for confounding variables. Similar results were observed for WC. Low and high levels of adiposity are associated with an increased likelihood of cognitive impairment in older adults in Chile.",

keywords = "Adiposity, Ageing, Cognitive impairment, Elderly, Obesity",

author = "Y. Concha-Cisternas and F. Lanuza and H. Waddell and Anne Sillars and Leiva, {A. M.} and C. Troncoso and Martinez, {M. A.} and M. Villagr{\'a}n and L. Mardones and M. Martorell and G. Nazar and N. Ulloa and Labra{\~n}a, {A. M.} and X. Diaz-Martinez and K. Sadarangani and C. Alvarez and R. Ramirez-Campillo and Alex Garrido-Mendez and Cristian Luarte and Frederick Ho and Gray, {Stuart R.} and F. Petermann-Rocha and C. Celis-Morales",

note = "Publisher Copyright: Copyright {\textcopyright} The Author(s) 2019 This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.",

year = "2019",

doi = "10.1017/jns.2019.24",

language = "English",

volume = "8",

journal = "Journal of Nutritional Science",

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Concha-Cisternas, Y, Lanuza, F, Waddell, H, Sillars, A, Leiva, AM, Troncoso, C, Martinez, MA, Villagrán, M, Mardones, L, Martorell, M, Nazar, G, Ulloa, N, Labraña, AM, Diaz-Martinez, X, Sadarangani, K, Alvarez, C, Ramirez-Campillo, R, Garrido-Mendez, A, Luarte, C, Ho, F, Gray, SR, Petermann-Rocha, F & Celis-Morales, C 2019, 'Association between adiposity levels and cognitive impairment in the Chilean older adult population', Journal of Nutritional Science, vol. 8, e33. https://doi.org/10.1017/jns.2019.24

TY - JOUR

T1 - Association between adiposity levels and cognitive impairment in the Chilean older adult population

AU - Concha-Cisternas, Y.

AU - Lanuza, F.

AU - Waddell, H.

AU - Sillars, Anne

AU - Leiva, A. M.

AU - Troncoso, C.

AU - Martinez, M. A.

AU - Villagrán, M.

AU - Mardones, L.

AU - Martorell, M.

AU - Nazar, G.

AU - Ulloa, N.

AU - Labraña, A. M.

AU - Diaz-Martinez, X.

AU - Sadarangani, K.

AU - Alvarez, C.

AU - Ramirez-Campillo, R.

AU - Garrido-Mendez, Alex

AU - Luarte, Cristian

AU - Ho, Frederick

AU - Gray, Stuart R.

AU - Petermann-Rocha, F.

AU - Celis-Morales, C.

N1 - Publisher Copyright: Copyright © The Author(s) 2019 This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.

PY - 2019

Y1 - 2019

N2 - Although both obesity and ageing are risk factors for cognitive impairment, there is no evidence in Chile on how obesity levels are associated with cognitive function. Therefore, the aim of the present study was to investigate the association between adiposity levels and cognitive impairment in older Chilean adults. This cross-sectional study includes 1384 participants, over 60 years of age, from the Chilean National Health Survey 2009-2010. Cognitive impairment was evaluated using the Mini-Mental State Examination. BMI and waist circumference (WC) were used as measures of adiposity. Compared with people with a normal BMI, the odds of cognitive impairment were higher in participants who were underweight (OR 4·44; 95 % CI 2·43, 6·45; P < 0·0001), overweight (OR 1·86; 95 % CI 1·06, 2·66; P = 0·031) and obese (OR 2·26; 95 % CI 1·31, 3·21; P = 0·003). The associations were robust after adjustment for confounding variables. Similar results were observed for WC. Low and high levels of adiposity are associated with an increased likelihood of cognitive impairment in older adults in Chile.

AB - Although both obesity and ageing are risk factors for cognitive impairment, there is no evidence in Chile on how obesity levels are associated with cognitive function. Therefore, the aim of the present study was to investigate the association between adiposity levels and cognitive impairment in older Chilean adults. This cross-sectional study includes 1384 participants, over 60 years of age, from the Chilean National Health Survey 2009-2010. Cognitive impairment was evaluated using the Mini-Mental State Examination. BMI and waist circumference (WC) were used as measures of adiposity. Compared with people with a normal BMI, the odds of cognitive impairment were higher in participants who were underweight (OR 4·44; 95 % CI 2·43, 6·45; P < 0·0001), overweight (OR 1·86; 95 % CI 1·06, 2·66; P = 0·031) and obese (OR 2·26; 95 % CI 1·31, 3·21; P = 0·003). The associations were robust after adjustment for confounding variables. Similar results were observed for WC. Low and high levels of adiposity are associated with an increased likelihood of cognitive impairment in older adults in Chile.

KW - Adiposity

KW - Ageing

KW - Cognitive impairment

KW - Elderly

KW - Obesity

UR - http://www.scopus.com/inward/record.url?scp=85073611474&partnerID=8YFLogxK

U2 - 10.1017/jns.2019.24

DO - 10.1017/jns.2019.24

M3 - Article

C2 - 31656624

AN - SCOPUS:85073611474

SN - 2048-6790

VL - 8

JO - Journal of Nutritional Science

JF - Journal of Nutritional Science

M1 - e33

ER -

Association between adiposity levels and cognitive impairment in the Chilean older adult population

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