Synthesis of Surfactant-Modified Poly (Acrylamide-co-Potassium Acrylate) Hydrogels and Its in vitro Release Studies

Sakey Ravindra; Antoine F. Mulaba-Bafubiandi; Vanarchi Rajineekanth; Kokkarachedu Varaprasad; Konduru Mohana Raju

doi:10.1080/03602559.2012.702255

Synthesis of Surfactant-Modified Poly (Acrylamide-co-Potassium Acrylate) Hydrogels and Its in vitro Release Studies

Sakey Ravindra^*, Antoine F. Mulaba-Bafubiandi, Vanarchi Rajineekanth, Kokkarachedu Varaprasad, Konduru Mohana Raju

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Abstract

In present investigation, a series of hydrogels, composed with Surfactant and poly(Acrylamide-co-Potassium acrylate), using Ammonium per sulfate(APS)/N,N,N ¹, N ¹-tetram ethylethylene diamine (TMEDA) initiating system and N,N ¹-methylenebisacrlyamide (MBA) as crosslinker. The prepared hydrogel was characterized by using Fourier transform infrared spectroscopy (FTIR), Thermo gravimetric analysis (TGA), Scanning electron microscopy (SEM). The controlled release characteristics of the matrices for Triprolidene hydrochloride (TH) were investigated in pH 7.4 media. Drug was released in a controlled manner up to 1400 min.

Original language	English
Pages (from-to)	1355-1360
Number of pages	6
Journal	Polymer - Plastics Technology and Engineering
Volume	51
Issue number	13
DOIs	https://doi.org/10.1080/03602559.2012.702255
State	Published - 2012
Externally published	Yes

Bibliographical note

Funding Information:
The authors (SR and KMR) thanks the University Grants Commission (UGC-SAP), Government of India, New Delhi for the partial financial support and AFM thanks the University of Johannesburg, South Africa for the partial financial support.

ASJC Scopus subject areas

Materials Science (miscellaneous)
General Chemical Engineering
Polymers and Plastics
Materials Chemistry

Access to Document

10.1080/03602559.2012.702255

Cite this

@article{5a106a89b35e4ce2b01b0b2feafe44fb,

title = "Synthesis of Surfactant-Modified Poly (Acrylamide-co-Potassium Acrylate) Hydrogels and Its in vitro Release Studies",

abstract = "In present investigation, a series of hydrogels, composed with Surfactant and poly(Acrylamide-co-Potassium acrylate), using Ammonium per sulfate(APS)/N,N,N 1, N 1-tetram ethylethylene diamine (TMEDA) initiating system and N,N 1-methylenebisacrlyamide (MBA) as crosslinker. The prepared hydrogel was characterized by using Fourier transform infrared spectroscopy (FTIR), Thermo gravimetric analysis (TGA), Scanning electron microscopy (SEM). The controlled release characteristics of the matrices for Triprolidene hydrochloride (TH) were investigated in pH 7.4 media. Drug was released in a controlled manner up to 1400 min.",

keywords = "Drug release, Hydrogel, Surfactant",

author = "Sakey Ravindra and Mulaba-Bafubiandi, {Antoine F.} and Vanarchi Rajineekanth and Kokkarachedu Varaprasad and Raju, {Konduru Mohana}",

note = "Funding Information: The authors (SR and KMR) thanks the University Grants Commission (UGC-SAP), Government of India, New Delhi for the partial financial support and AFM thanks the University of Johannesburg, South Africa for the partial financial support.",

year = "2012",

month = sep,

doi = "10.1080/03602559.2012.702255",

language = "English",

volume = "51",

pages = "1355--1360",

journal = "Polymer - Plastics Technology and Engineering",

issn = "0360-2559",

publisher = "Taylor and Francis Ltd.",

number = "13",

}

TY - JOUR

T1 - Synthesis of Surfactant-Modified Poly (Acrylamide-co-Potassium Acrylate) Hydrogels and Its in vitro Release Studies

AU - Ravindra, Sakey

AU - Mulaba-Bafubiandi, Antoine F.

AU - Rajineekanth, Vanarchi

AU - Varaprasad, Kokkarachedu

AU - Raju, Konduru Mohana

N1 - Funding Information: The authors (SR and KMR) thanks the University Grants Commission (UGC-SAP), Government of India, New Delhi for the partial financial support and AFM thanks the University of Johannesburg, South Africa for the partial financial support.

PY - 2012/9

Y1 - 2012/9

N2 - In present investigation, a series of hydrogels, composed with Surfactant and poly(Acrylamide-co-Potassium acrylate), using Ammonium per sulfate(APS)/N,N,N 1, N 1-tetram ethylethylene diamine (TMEDA) initiating system and N,N 1-methylenebisacrlyamide (MBA) as crosslinker. The prepared hydrogel was characterized by using Fourier transform infrared spectroscopy (FTIR), Thermo gravimetric analysis (TGA), Scanning electron microscopy (SEM). The controlled release characteristics of the matrices for Triprolidene hydrochloride (TH) were investigated in pH 7.4 media. Drug was released in a controlled manner up to 1400 min.

AB - In present investigation, a series of hydrogels, composed with Surfactant and poly(Acrylamide-co-Potassium acrylate), using Ammonium per sulfate(APS)/N,N,N 1, N 1-tetram ethylethylene diamine (TMEDA) initiating system and N,N 1-methylenebisacrlyamide (MBA) as crosslinker. The prepared hydrogel was characterized by using Fourier transform infrared spectroscopy (FTIR), Thermo gravimetric analysis (TGA), Scanning electron microscopy (SEM). The controlled release characteristics of the matrices for Triprolidene hydrochloride (TH) were investigated in pH 7.4 media. Drug was released in a controlled manner up to 1400 min.

KW - Drug release

KW - Hydrogel

KW - Surfactant

UR - http://www.scopus.com/inward/record.url?scp=84867226929&partnerID=8YFLogxK

U2 - 10.1080/03602559.2012.702255

DO - 10.1080/03602559.2012.702255

M3 - Article

AN - SCOPUS:84867226929

SN - 0360-2559

VL - 51

SP - 1355

EP - 1360

JO - Polymer - Plastics Technology and Engineering

JF - Polymer - Plastics Technology and Engineering

IS - 13

ER -

Synthesis of Surfactant-Modified Poly (Acrylamide-co-Potassium Acrylate) Hydrogels and Its in vitro Release Studies

Abstract

Bibliographical note

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this