Abstract
To strengthen research ethics systemically, the Pan American Health Organization (PAHO) devised a strategy that includes objectives and indicators to address core components of research ethics systems. We assessed 22 countries in Latin America and the Caribbean using these indicators. Most countries have adopted legal instruments to govern research with human participants and have implemented national bodies tasked with the oversight of research ethics committees. However, performance with regard to ethics training policies and clinical trial registration was less advanced, and efforts to adopt policies on responsible conduct of research and accelerated ethics review of emergency research did not meet the PAHO objectives in most countries. We discuss the pending challenges and provide recommendations aimed at helping countries from Latin America and the Caribbean to achieve the indicators, and, more generally, to strengthen research ethics with a systemic approach.
| Original language | English |
|---|---|
| Pages (from-to) | e1204-e1208 |
| Journal | The Lancet Global Health |
| Volume | 10 |
| Issue number | 8 |
| DOIs | |
| State | Published - 2022 |
Bibliographical note
Funding Information:We thank Anisa Hasan-Granier for her help during the initial stage of this project. We also thank bioethicists, health authorities, and members of research ethics committees in the Latin America and the Caribbean region for their invaluable collaboration and input throughout this project. This work was partially funded by a grant from the Wellcome Trust (number 220028/Z/19/Z). BA was supported during part of the preparation of this work by the Intramural Program at the National Institutes of Health Clinical Center.
Publisher Copyright:
© 2022 Pan American Health Organization. Published by Elsevier Ltd. This is an Open Access article under the CC BY-NC-ND 4.0 license
ASJC Scopus subject areas
- General Medicine
