Functional evaluation of human ClC-2 chloride channel mutations associated with idiopathic generalized epilepsies

Biochemistry, Genetics and Molecular Biology

• Wild Type 100%
• Chloride Channel 100%
• Exon 66%
• Adenosine Triphosphate 66%
• Electric Potential 66%
• Patch Clamp 33%
• Stop Codon 33%
• Minigene 33%
• Confocal Microscopy 33%
• Homeostasis 33%
• Cell Membrane 33%
• HEK 293 Cells 33%
• Intron 33%
• Astrocyte 33%
• Adenosine Monophosphate 33%
• Missense Mutation 33%
• Loss of Function Mutation 33%
• Haploinsufficiency 33%
• CLCN2 33%
• Messenger RNA 33%
• Gamma-Aminobutyric Acid 33%

Neuroscience

• Chloride Channel 100%
• Primary Generalized Epilepsy 100%
• Adenosine Triphosphate 66%
• Exon 66%
• Confocal Microscopy 33%
• Adenosine Monophosphate 33%
• In Vitro 33%
• Astrocyte 33%
• Cell Membrane 33%
• Patch Clamp 33%
• Gamma-Aminobutyric Acid 33%
• HEK 293 Cells 33%
• Intron 33%
• Loss of Function Mutation 33%
• Missense Mutation 33%
• Haploinsufficiency 33%
• CLCN2 33%
• Stop Codon 33%
• Messenger RNA 33%