Development of novel biodegradable Au nanocomposite hydrogels based on wheat: For inactivation of bacteria

Tippabattini Jayaramudu; Gownolla Malegowd Raghavendra; Kokkarachedu Varaprasad; Rotimi Sadiku; Konduru Mohana Raju

doi:10.1016/j.carbpol.2012.12.006

Development of novel biodegradable Au nanocomposite hydrogels based on wheat: For inactivation of bacteria

Tippabattini Jayaramudu, Gownolla Malegowd Raghavendra, Kokkarachedu Varaprasad^*, Rotimi Sadiku, Konduru Mohana Raju

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

129 Scopus citations

Abstract

The design and fabrication of novel biodegradable gold nanocomposites hydrogels were developed as antibacterial agent. Biodegradable gold nanocomposite hydrogels were developed by using acrylamide (AM) and wheat protein isolate (WPI). The gold nanoparticles were prepared as a gold colloid by reducing HAuCl₄·XH₂O with leaf extracts of Azadirachta indica (neem leaf) that formed hydrogel network. The characterization of developed biodegradable hydrogels were studied using fourier transforms infrared (FTIR) spectroscopy, ultraviolet-visible (UV-vis) spectroscopy, X-ray diffraction (XRD), thermo-gravimetric analysis (TGA), differential scanning calorimetry (DSC), scanning electron microscopy-energy dispersive spectroscopy (SEM-EDS) and transmission electron microscopy (TEM). The biodegradable gold nanoparticle composite hydrogels developed were tested for antibacterial properties. The results indicate that these biodegradable gold nanocomposite hydrogels can be used as potential candidates for antibacterial applications.

Original language	English
Pages (from-to)	2193-2200
Number of pages	8
Journal	Carbohydrate Polymers
Volume	92
Issue number	2
DOIs	https://doi.org/10.1016/j.carbpol.2012.12.006
State	Published - 2013
Externally published	Yes

Bibliographical note

Funding Information:
One of the authors (TJ) thanks the UGC , New Delhi, INDIA for the award of JRF under UGC-BSR Meritorious Fellowship Scheme.

ASJC Scopus subject areas

Organic Chemistry
Polymers and Plastics
Materials Chemistry

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title = "Development of novel biodegradable Au nanocomposite hydrogels based on wheat: For inactivation of bacteria",

abstract = "The design and fabrication of novel biodegradable gold nanocomposites hydrogels were developed as antibacterial agent. Biodegradable gold nanocomposite hydrogels were developed by using acrylamide (AM) and wheat protein isolate (WPI). The gold nanoparticles were prepared as a gold colloid by reducing HAuCl4·XH2O with leaf extracts of Azadirachta indica (neem leaf) that formed hydrogel network. The characterization of developed biodegradable hydrogels were studied using fourier transforms infrared (FTIR) spectroscopy, ultraviolet-visible (UV-vis) spectroscopy, X-ray diffraction (XRD), thermo-gravimetric analysis (TGA), differential scanning calorimetry (DSC), scanning electron microscopy-energy dispersive spectroscopy (SEM-EDS) and transmission electron microscopy (TEM). The biodegradable gold nanoparticle composite hydrogels developed were tested for antibacterial properties. The results indicate that these biodegradable gold nanocomposite hydrogels can be used as potential candidates for antibacterial applications.",

keywords = "Antibacterial and hydrogels, Azadirachta indica (neem leaf), Biodegradable, Wheat protein isolate",

author = "Tippabattini Jayaramudu and Raghavendra, {Gownolla Malegowd} and Kokkarachedu Varaprasad and Rotimi Sadiku and Raju, {Konduru Mohana}",

note = "Funding Information: One of the authors (TJ) thanks the UGC , New Delhi, INDIA for the award of JRF under UGC-BSR Meritorious Fellowship Scheme.",

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doi = "10.1016/j.carbpol.2012.12.006",

language = "English",

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AU - Varaprasad, Kokkarachedu

AU - Sadiku, Rotimi

AU - Raju, Konduru Mohana

N1 - Funding Information: One of the authors (TJ) thanks the UGC , New Delhi, INDIA for the award of JRF under UGC-BSR Meritorious Fellowship Scheme.

PY - 2013/2/15

Y1 - 2013/2/15

N2 - The design and fabrication of novel biodegradable gold nanocomposites hydrogels were developed as antibacterial agent. Biodegradable gold nanocomposite hydrogels were developed by using acrylamide (AM) and wheat protein isolate (WPI). The gold nanoparticles were prepared as a gold colloid by reducing HAuCl4·XH2O with leaf extracts of Azadirachta indica (neem leaf) that formed hydrogel network. The characterization of developed biodegradable hydrogels were studied using fourier transforms infrared (FTIR) spectroscopy, ultraviolet-visible (UV-vis) spectroscopy, X-ray diffraction (XRD), thermo-gravimetric analysis (TGA), differential scanning calorimetry (DSC), scanning electron microscopy-energy dispersive spectroscopy (SEM-EDS) and transmission electron microscopy (TEM). The biodegradable gold nanoparticle composite hydrogels developed were tested for antibacterial properties. The results indicate that these biodegradable gold nanocomposite hydrogels can be used as potential candidates for antibacterial applications.

AB - The design and fabrication of novel biodegradable gold nanocomposites hydrogels were developed as antibacterial agent. Biodegradable gold nanocomposite hydrogels were developed by using acrylamide (AM) and wheat protein isolate (WPI). The gold nanoparticles were prepared as a gold colloid by reducing HAuCl4·XH2O with leaf extracts of Azadirachta indica (neem leaf) that formed hydrogel network. The characterization of developed biodegradable hydrogels were studied using fourier transforms infrared (FTIR) spectroscopy, ultraviolet-visible (UV-vis) spectroscopy, X-ray diffraction (XRD), thermo-gravimetric analysis (TGA), differential scanning calorimetry (DSC), scanning electron microscopy-energy dispersive spectroscopy (SEM-EDS) and transmission electron microscopy (TEM). The biodegradable gold nanoparticle composite hydrogels developed were tested for antibacterial properties. The results indicate that these biodegradable gold nanocomposite hydrogels can be used as potential candidates for antibacterial applications.

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Development of novel biodegradable Au nanocomposite hydrogels based on wheat: For inactivation of bacteria

Abstract

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ASJC Scopus subject areas

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