Development of Gelatin Based Inorganic Nanocomposite Hydrogels for Inactivation of Bacteria

P. Ranga Reddy; K. Varaprasad; Rotimi Sadiku; Koduri Ramam; G. Venkata Subba Reddy; K. Mohana Raju; N. Subbarami Reddy

doi:10.1007/s10904-013-9886-x

Development of Gelatin Based Inorganic Nanocomposite Hydrogels for Inactivation of Bacteria

P. Ranga Reddy, K. Varaprasad^*, Rotimi Sadiku, Koduri Ramam, G. Venkata Subba Reddy, K. Mohana Raju, N. Subbarami Reddy

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

32 Scopus citations

Abstract

In this investigation, silver nanocomposite hydrogels were developed by using acrylamide and biodegradable gelatin. Silver nanoparticles were generated throughout the hydrogel networks using in situ method by incorporating Ag⁺ ions and the subsequent treatment with sodium borohydride. The effect of gelatin on the swelling studies was investigated. The hydrogel synthesized silver nanocomposites were characterized by using Fourier transform infrared, UV-Visible spectroscopy, X-ray diffraction, thermogravimetric analysis, scanning electron and transmission electron microscopy techniques. The biodegradable gelatin-based silver nanocomposite hydrogels were tested for antibacterial properties. The results indicate that these biodegradable silver nanocomposite hydrogels can be useful in medical applications, as antibacterial agents.

Original language	English
Pages (from-to)	1054-1060
Number of pages	7
Journal	Journal of Inorganic and Organometallic Polymers and Materials
Volume	23
Issue number	5
DOIs	https://doi.org/10.1007/s10904-013-9886-x
State	Published - 2013
Externally published	Yes

Bibliographical note

Funding Information:
Acknowledgments Two of the authors (KVP & KRM) thank the Fondecyt Proyecto No: 3130748 & 1110583 Chile (South America). The Authors (PRR & NSR) are grateful to the University Grants Commission, New Delhi, India for the financial support in the form of a Major Research Project.

ASJC Scopus subject areas

Polymers and Plastics
Materials Chemistry

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10.1007/s10904-013-9886-x

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title = "Development of Gelatin Based Inorganic Nanocomposite Hydrogels for Inactivation of Bacteria",

abstract = "In this investigation, silver nanocomposite hydrogels were developed by using acrylamide and biodegradable gelatin. Silver nanoparticles were generated throughout the hydrogel networks using in situ method by incorporating Ag+ ions and the subsequent treatment with sodium borohydride. The effect of gelatin on the swelling studies was investigated. The hydrogel synthesized silver nanocomposites were characterized by using Fourier transform infrared, UV-Visible spectroscopy, X-ray diffraction, thermogravimetric analysis, scanning electron and transmission electron microscopy techniques. The biodegradable gelatin-based silver nanocomposite hydrogels were tested for antibacterial properties. The results indicate that these biodegradable silver nanocomposite hydrogels can be useful in medical applications, as antibacterial agents.",

keywords = "Antimicrobial and hydrogel, Gelatin, Inorganic nanocomposites, Silver",

author = "Reddy, {P. Ranga} and K. Varaprasad and Rotimi Sadiku and Koduri Ramam and Reddy, {G. Venkata Subba} and Raju, {K. Mohana} and Reddy, {N. Subbarami}",

note = "Funding Information: Acknowledgments Two of the authors (KVP & KRM) thank the Fondecyt Proyecto No: 3130748 & 1110583 Chile (South America). The Authors (PRR & NSR) are grateful to the University Grants Commission, New Delhi, India for the financial support in the form of a Major Research Project.",

year = "2013",

month = sep,

doi = "10.1007/s10904-013-9886-x",

language = "English",

volume = "23",

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journal = "Journal of Inorganic and Organometallic Polymers and Materials",

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T1 - Development of Gelatin Based Inorganic Nanocomposite Hydrogels for Inactivation of Bacteria

AU - Reddy, P. Ranga

AU - Varaprasad, K.

AU - Sadiku, Rotimi

AU - Ramam, Koduri

AU - Reddy, G. Venkata Subba

AU - Raju, K. Mohana

AU - Reddy, N. Subbarami

N1 - Funding Information: Acknowledgments Two of the authors (KVP & KRM) thank the Fondecyt Proyecto No: 3130748 & 1110583 Chile (South America). The Authors (PRR & NSR) are grateful to the University Grants Commission, New Delhi, India for the financial support in the form of a Major Research Project.

PY - 2013/9

Y1 - 2013/9

N2 - In this investigation, silver nanocomposite hydrogels were developed by using acrylamide and biodegradable gelatin. Silver nanoparticles were generated throughout the hydrogel networks using in situ method by incorporating Ag+ ions and the subsequent treatment with sodium borohydride. The effect of gelatin on the swelling studies was investigated. The hydrogel synthesized silver nanocomposites were characterized by using Fourier transform infrared, UV-Visible spectroscopy, X-ray diffraction, thermogravimetric analysis, scanning electron and transmission electron microscopy techniques. The biodegradable gelatin-based silver nanocomposite hydrogels were tested for antibacterial properties. The results indicate that these biodegradable silver nanocomposite hydrogels can be useful in medical applications, as antibacterial agents.

AB - In this investigation, silver nanocomposite hydrogels were developed by using acrylamide and biodegradable gelatin. Silver nanoparticles were generated throughout the hydrogel networks using in situ method by incorporating Ag+ ions and the subsequent treatment with sodium borohydride. The effect of gelatin on the swelling studies was investigated. The hydrogel synthesized silver nanocomposites were characterized by using Fourier transform infrared, UV-Visible spectroscopy, X-ray diffraction, thermogravimetric analysis, scanning electron and transmission electron microscopy techniques. The biodegradable gelatin-based silver nanocomposite hydrogels were tested for antibacterial properties. The results indicate that these biodegradable silver nanocomposite hydrogels can be useful in medical applications, as antibacterial agents.

KW - Antimicrobial and hydrogel

KW - Gelatin

KW - Inorganic nanocomposites

KW - Silver

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SP - 1054

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JO - Journal of Inorganic and Organometallic Polymers and Materials

JF - Journal of Inorganic and Organometallic Polymers and Materials

IS - 5

ER -

Development of Gelatin Based Inorganic Nanocomposite Hydrogels for Inactivation of Bacteria

Abstract

Bibliographical note

ASJC Scopus subject areas

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