Development and Characterization of Curcumin Loaded Silver Nanoparticle Hydrogels for Antibacterial and Drug Delivery Applications

Sakey Ravindra; Antoine F. Mulaba-Bafubiandi; V. Rajinikanth; K. Varaprasad; N. Narayana Reddy; K. Mohana Raju

doi:10.1007/s10904-012-9734-4

Development and Characterization of Curcumin Loaded Silver Nanoparticle Hydrogels for Antibacterial and Drug Delivery Applications

Sakey Ravindra^*, Antoine F. Mulaba-Bafubiandi, V. Rajinikanth, K. Varaprasad, N. Narayana Reddy, K. Mohana Raju

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

66 Scopus citations

Abstract

The present work involves the development of curcumin loaded silver hydrogel nanocomposites based on acrylamide and 2-acrylamido-2-methyl propanesulfonic acid, as a template by redox co-polymerization in the presence of hydrophilic crosslinker N,N ¹-methylenebisacrylamide. Silver nitrate was taken as the metal precursor and sodium borohydride as a reducing agent. The formation of silver nanoparticles was monitored using UV-Vis absorption spectroscopy. The developed hydrogel silver nanocomposites (HSNC) were characterized by FTIR, UV-Vis, thermogravimetric analysis, scanning electron microscopy and transmission electron microscopy. The curcumin loading and release characteristics were performed for different hydrogel systems. The developed HSNCs were evaluated for preliminary antibacterial applications.

Original language	English
Pages (from-to)	1254-1262
Number of pages	9
Journal	Journal of Inorganic and Organometallic Polymers and Materials
Volume	22
Issue number	6
DOIs	https://doi.org/10.1007/s10904-012-9734-4
State	Published - 2012
Externally published	Yes

Bibliographical note

Funding Information:
Acknowledgments The authors (SR & KMR) thanks the University Grants Commission (UGC-SAP), Government of India, New Delhi for the partial financial support and AFM-B thanks the University of Johannesburg, South Africa for the partial financial support.

ASJC Scopus subject areas

Polymers and Plastics
Materials Chemistry

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Ravindra, S., Mulaba-Bafubiandi, A. F., Rajinikanth, V., Varaprasad, K., Narayana Reddy, N., & Mohana Raju, K. (2012). Development and Characterization of Curcumin Loaded Silver Nanoparticle Hydrogels for Antibacterial and Drug Delivery Applications. Journal of Inorganic and Organometallic Polymers and Materials, 22(6), 1254-1262. https://doi.org/10.1007/s10904-012-9734-4

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title = "Development and Characterization of Curcumin Loaded Silver Nanoparticle Hydrogels for Antibacterial and Drug Delivery Applications",

abstract = "The present work involves the development of curcumin loaded silver hydrogel nanocomposites based on acrylamide and 2-acrylamido-2-methyl propanesulfonic acid, as a template by redox co-polymerization in the presence of hydrophilic crosslinker N,N 1-methylenebisacrylamide. Silver nitrate was taken as the metal precursor and sodium borohydride as a reducing agent. The formation of silver nanoparticles was monitored using UV-Vis absorption spectroscopy. The developed hydrogel silver nanocomposites (HSNC) were characterized by FTIR, UV-Vis, thermogravimetric analysis, scanning electron microscopy and transmission electron microscopy. The curcumin loading and release characteristics were performed for different hydrogel systems. The developed HSNCs were evaluated for preliminary antibacterial applications.",

keywords = "Antibacterial activity, Hydrogel network, Silver nanoparticles",

author = "Sakey Ravindra and Mulaba-Bafubiandi, {Antoine F.} and V. Rajinikanth and K. Varaprasad and {Narayana Reddy}, N. and {Mohana Raju}, K.",

note = "Funding Information: Acknowledgments The authors (SR & KMR) thanks the University Grants Commission (UGC-SAP), Government of India, New Delhi for the partial financial support and AFM-B thanks the University of Johannesburg, South Africa for the partial financial support.",

year = "2012",

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doi = "10.1007/s10904-012-9734-4",

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Ravindra, S, Mulaba-Bafubiandi, AF, Rajinikanth, V, Varaprasad, K, Narayana Reddy, N & Mohana Raju, K 2012, 'Development and Characterization of Curcumin Loaded Silver Nanoparticle Hydrogels for Antibacterial and Drug Delivery Applications', Journal of Inorganic and Organometallic Polymers and Materials, vol. 22, no. 6, pp. 1254-1262. https://doi.org/10.1007/s10904-012-9734-4

Development and Characterization of Curcumin Loaded Silver Nanoparticle Hydrogels for Antibacterial and Drug Delivery Applications. / Ravindra, Sakey; Mulaba-Bafubiandi, Antoine F.; Rajinikanth, V. et al.
In: Journal of Inorganic and Organometallic Polymers and Materials, Vol. 22, No. 6, 11.2012, p. 1254-1262.

Research output: Contribution to journal › Article › peer-review

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T1 - Development and Characterization of Curcumin Loaded Silver Nanoparticle Hydrogels for Antibacterial and Drug Delivery Applications

AU - Ravindra, Sakey

AU - Mulaba-Bafubiandi, Antoine F.

AU - Rajinikanth, V.

AU - Varaprasad, K.

AU - Narayana Reddy, N.

AU - Mohana Raju, K.

N1 - Funding Information: Acknowledgments The authors (SR & KMR) thanks the University Grants Commission (UGC-SAP), Government of India, New Delhi for the partial financial support and AFM-B thanks the University of Johannesburg, South Africa for the partial financial support.

PY - 2012/11

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N2 - The present work involves the development of curcumin loaded silver hydrogel nanocomposites based on acrylamide and 2-acrylamido-2-methyl propanesulfonic acid, as a template by redox co-polymerization in the presence of hydrophilic crosslinker N,N 1-methylenebisacrylamide. Silver nitrate was taken as the metal precursor and sodium borohydride as a reducing agent. The formation of silver nanoparticles was monitored using UV-Vis absorption spectroscopy. The developed hydrogel silver nanocomposites (HSNC) were characterized by FTIR, UV-Vis, thermogravimetric analysis, scanning electron microscopy and transmission electron microscopy. The curcumin loading and release characteristics were performed for different hydrogel systems. The developed HSNCs were evaluated for preliminary antibacterial applications.

AB - The present work involves the development of curcumin loaded silver hydrogel nanocomposites based on acrylamide and 2-acrylamido-2-methyl propanesulfonic acid, as a template by redox co-polymerization in the presence of hydrophilic crosslinker N,N 1-methylenebisacrylamide. Silver nitrate was taken as the metal precursor and sodium borohydride as a reducing agent. The formation of silver nanoparticles was monitored using UV-Vis absorption spectroscopy. The developed hydrogel silver nanocomposites (HSNC) were characterized by FTIR, UV-Vis, thermogravimetric analysis, scanning electron microscopy and transmission electron microscopy. The curcumin loading and release characteristics were performed for different hydrogel systems. The developed HSNCs were evaluated for preliminary antibacterial applications.

KW - Antibacterial activity

KW - Hydrogel network

KW - Silver nanoparticles

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ER -

Development and Characterization of Curcumin Loaded Silver Nanoparticle Hydrogels for Antibacterial and Drug Delivery Applications

Abstract

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