Antibiotic copper oxide-curcumin nanomaterials for antibacterial applications

Kokkarachedu Varaprasad; Matias López; Dariela Núñez; Tippabattini Jayaramudu; Emmanuel Rotimi Sadiku; Chandrasekaran Karthikeyan; Patricio Oyarzúnc

doi:10.1016/j.molliq.2019.112353

Antibiotic copper oxide-curcumin nanomaterials for antibacterial applications

Kokkarachedu Varaprasad^*, Matias López, Dariela Núñez, Tippabattini Jayaramudu, Emmanuel Rotimi Sadiku, Chandrasekaran Karthikeyan, Patricio Oyarzúnc

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

58 Scopus citations

Abstract

In this investigation, novel antibiotic core-shell copper oxide-curcumin nanocomposite materials were designed and developed for biomedical applications. The antibiotic nanocomposite materials were synthesized by using sonication technique. In this process, the bandgap of the nanomaterial was controlled by using CuO and it was confirmed by UV-DRS. The formation of an antibiotic core-shell nanostructures and their surface morphologies were studied with XRD, SEM/TEM. EDS and ATR-FTIR confirmed the existence of copper oxide and biomolecule Cum in the antibiotic nanocomposites. In addition, it was recognised that Cum regulated sufficiently, the CuO antibacterial performance towards selected bacteria, viz: Escherichia coli, Staphylococcus aureus, Shigella dysenteriae and Streptococcus pneumoniae. Moreover, the nanomaterials synthesized did show noble antibacterial activity than the standard amoxicillin antibiotic. The finding of this investigation gives unalloyed support that the antibiotic nanocomposites can be highly promising materials for advanced biomedical applications.

Original language	English
Article number	112353
Journal	Journal of Molecular Liquids
Volume	300
DOIs	https://doi.org/10.1016/j.molliq.2019.112353
State	Published - 2020

Bibliographical note

Publisher Copyright:
© 2018 Elsevier B.V.

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Atomic and Molecular Physics, and Optics
Condensed Matter Physics
Spectroscopy
Physical and Theoretical Chemistry
Materials Chemistry

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title = "Antibiotic copper oxide-curcumin nanomaterials for antibacterial applications",

abstract = "In this investigation, novel antibiotic core-shell copper oxide-curcumin nanocomposite materials were designed and developed for biomedical applications. The antibiotic nanocomposite materials were synthesized by using sonication technique. In this process, the bandgap of the nanomaterial was controlled by using CuO and it was confirmed by UV-DRS. The formation of an antibiotic core-shell nanostructures and their surface morphologies were studied with XRD, SEM/TEM. EDS and ATR-FTIR confirmed the existence of copper oxide and biomolecule Cum in the antibiotic nanocomposites. In addition, it was recognised that Cum regulated sufficiently, the CuO antibacterial performance towards selected bacteria, viz: Escherichia coli, Staphylococcus aureus, Shigella dysenteriae and Streptococcus pneumoniae. Moreover, the nanomaterials synthesized did show noble antibacterial activity than the standard amoxicillin antibiotic. The finding of this investigation gives unalloyed support that the antibiotic nanocomposites can be highly promising materials for advanced biomedical applications.",

keywords = "Antibacterial activity, Antibiotics, CuO nanoparticles, Curcumin",

author = "Kokkarachedu Varaprasad and Matias L{\'o}pez and Dariela N{\'u}{\~n}ez and Tippabattini Jayaramudu and Sadiku, {Emmanuel Rotimi} and Chandrasekaran Karthikeyan and Patricio Oyarz{\'u}nc",

note = "Publisher Copyright: {\textcopyright} 2018 Elsevier B.V.",

year = "2020",

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doi = "10.1016/j.molliq.2019.112353",

language = "English",

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T1 - Antibiotic copper oxide-curcumin nanomaterials for antibacterial applications

AU - Varaprasad, Kokkarachedu

AU - López, Matias

AU - Núñez, Dariela

AU - Jayaramudu, Tippabattini

AU - Sadiku, Emmanuel Rotimi

AU - Karthikeyan, Chandrasekaran

AU - Oyarzúnc, Patricio

PY - 2020/2/15

Y1 - 2020/2/15

N2 - In this investigation, novel antibiotic core-shell copper oxide-curcumin nanocomposite materials were designed and developed for biomedical applications. The antibiotic nanocomposite materials were synthesized by using sonication technique. In this process, the bandgap of the nanomaterial was controlled by using CuO and it was confirmed by UV-DRS. The formation of an antibiotic core-shell nanostructures and their surface morphologies were studied with XRD, SEM/TEM. EDS and ATR-FTIR confirmed the existence of copper oxide and biomolecule Cum in the antibiotic nanocomposites. In addition, it was recognised that Cum regulated sufficiently, the CuO antibacterial performance towards selected bacteria, viz: Escherichia coli, Staphylococcus aureus, Shigella dysenteriae and Streptococcus pneumoniae. Moreover, the nanomaterials synthesized did show noble antibacterial activity than the standard amoxicillin antibiotic. The finding of this investigation gives unalloyed support that the antibiotic nanocomposites can be highly promising materials for advanced biomedical applications.

AB - In this investigation, novel antibiotic core-shell copper oxide-curcumin nanocomposite materials were designed and developed for biomedical applications. The antibiotic nanocomposite materials were synthesized by using sonication technique. In this process, the bandgap of the nanomaterial was controlled by using CuO and it was confirmed by UV-DRS. The formation of an antibiotic core-shell nanostructures and their surface morphologies were studied with XRD, SEM/TEM. EDS and ATR-FTIR confirmed the existence of copper oxide and biomolecule Cum in the antibiotic nanocomposites. In addition, it was recognised that Cum regulated sufficiently, the CuO antibacterial performance towards selected bacteria, viz: Escherichia coli, Staphylococcus aureus, Shigella dysenteriae and Streptococcus pneumoniae. Moreover, the nanomaterials synthesized did show noble antibacterial activity than the standard amoxicillin antibiotic. The finding of this investigation gives unalloyed support that the antibiotic nanocomposites can be highly promising materials for advanced biomedical applications.

KW - Antibacterial activity

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KW - CuO nanoparticles

KW - Curcumin

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JO - Journal of Molecular Liquids

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Antibiotic copper oxide-curcumin nanomaterials for antibacterial applications

Abstract

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ASJC Scopus subject areas

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