A Novel Biodegradable Green Poly(l-Aspartic Acid-Citric Acid) Copolymer for Antimicrobial Applications

N. Mithil Kumar, K. Varaprasad, K. Madhusudana Rao, A. Suresh Babu, M. Srinivasulu, S. Venkata Naidu

Research output: Contribution to journalArticlepeer-review

27 Scopus citations

Abstract

Poly (l-aspartic acid-citric acid) green copolymers were developed using thermal polymerization of aspartic acid (ASP) and citric acid (CA) followed by direct bulk melt condensation technique. Antibacterial properties of copolymer of aspartic acid based were investigated as a function of citric acid content. This study is focused on the microorganism inhibition performance of aspartic acid based copolymers. Results showed that inhibition properties increase with increasing citric acid content. Characterization of obtained copolymers was carried out with the help of infrared absorption spectra (FTIR), x-ray diffraction (XRD), differential scanning calorimetry (DSC) and thermo gravimetric analysis (TGA). The antibacterial activity of copolymers against bacteria like E-coli, Bacillus and pseudomonas was investigated. The copolymers showed excellent antimicrobial activities against three types of microorganisms. Overall studies indicated that the above copolymers possess a broad wound dressing activity against above three types of bacteria and may be useful as antibacterial agents.

Original languageEnglish
Pages (from-to)17-22
Number of pages6
JournalJournal of Polymers and the Environment
Volume20
Issue number1
DOIs
StatePublished - 2012
Externally publishedYes

Bibliographical note

Funding Information:
Acknowledgments N. Mithil Kumar thanks the University Grants Commission (UGC), Government of India, New Delhi for the financial support is the from meritorious fellowship.

ASJC Scopus subject areas

  • Environmental Engineering
  • Polymers and Plastics
  • Materials Chemistry

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