Personal profile
Teaching
She has been dedicated to teaching cell biology, with a special emphasis on the mechanisms associated with aging and the immune system. In addition, She has participated in courses related to general immunology and neuroimmunology. The knowledge applied in these courses is closely related to the research line developed in the laboratory.
Research interests
The area of interest of our laboratory group is to understand the changes that occur in the functions of the immune system due to the effects of time. In other words, how certain proteins present in immune system cells change in expression and therefore, in function, leading to changes in the function of immune system cells. We are mainly focused on analyzing the cells of the innate immune system corresponding to macrophages. We are interested in understanding how these changes in protein levels lead to pathologies in different systems such as the central nervous system and its effect on neurodegeneration and tissue regeneration, as well as the metabolic changes that occur systemically and in relation to the accumulation of fats.
Personal profile
She is researching the aging process and the proteins that can recognize a cell's own mutated DNA or exogenous DNA from viruses and bacteria. These proteins participate in protection against pathogens and also prevent tumor development. However, little is known about their role during aging. In the laboratory where she works, she investigates how these messages change over time and how they could be related to inflammatory diseases that affect metabolism, tissue regeneration, and the development of neurodegeneration.
External positions
Universidad Mayor, Santiago, Chile
2020 → 2021
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Changes in transposable elements expression in male and female mice liver throughout aging
Hernández , B., Murgas Alcaíno, P. P. & Riadi, G., 2026, In: GeroScience. 47, 2, 10 p., https://doi.org/10.1007/s11357-025-02065-y.Research output: Contribution to journal › Article › peer-review
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Lifelong cGAS deficiency leads to altered lipid storage and cholesterol homeostasis
Carrillanca, D., Riquelme, I., Mansilla-Jaramillo, M., Sánchez-Pérez, C., Monterroza, A., Lepio, N., Rojas, F., Cancino, G. I. & Murgas Alcaíno, P. P., 2026, In: Biological Research. 59, 1, 12.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Electrospun Polyvinyl Alcohol/Sodium Alginate Nanocomposite Dressings Loaded with ZnO and Bioglass: Characterization, Antibacterial Activity, and Cytocompatibility
Ortiz, J. A., Sepúlveda, F. A., Flores , S., Saavedra, M., Sáez-Silva, S., Jiménez, T., Murgas Alcaíno, P. P., Troncoso , S., Sanhueza, C., Ulloa, M. T., Torres, L. P., Ahumada, M., Corrales , T., Plaza, H. & Zapata, P. A., 2025, In: Polymers. 17, 16, p. 2185 25 p.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations1 Downloads (Pure) -
Loss of Stimulator of Interferon Genes (STING) Promotes Accumulation of Cholesterol and Tri-glycerides Throughout Life in Mice
Riquelme, I., Carrillanca, D., Sánchez, C., Monterroza, A., Hernández , B., Riadi, G., Cancino, G. I. & Murgas Alcaíno, P. P., 2025, In: Biological Research. 58, 1, p. 1 17 p., 45.Translated title of the contribution :La pérdida de la proteína Estimuladora de Genes de Interferón (STING) promueve la acumulación de Colesterol y Triglicéridos a lo largo de la vida de ratones Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Scopus citations12 Downloads (Pure) -
Oxidative stress promotes cytotoxicity in human cancer cell lines exposed to Escallonia spp. extracts
Jara-Gutiérrez, C., Mercado, L., Paz-Araos, M., Howard, C., Parraga, M., Escobar, C., Mellado, M., Madrid, A., Montenegro, I., Santana, P., Murgas, P., Jimenez-Jara, C., González-Olivares, L. G., Ahumada, M. & Villena, J., 2024, In: BMC Complementary and Alternative Medicine. 24, 1, 38.Research output: Contribution to journal › Article › peer-review
Open Access12 Scopus citations