Paola Patricia Murgas Alcaíno, PhD

    Calculated based on the number of publications stored in Pure and citations from PlumX
    Calculated based on number of publications stored in Pure and citations from Scopus
    Calculated based on number of publications stored in Pure and citations from Scopus
    20102024

    Research activity per year

    Personal profile

    Teaching

    She has been dedicated to teaching cell biology, with a special emphasis on the mechanisms associated with aging and the immune system. In addition, She has participated in courses related to general immunology and neuroimmunology. The knowledge applied in these courses is closely related to the research line developed in the laboratory.

    Research interests

    The area of interest of our laboratory group is to understand the changes that occur in the functions of the immune system due to the effects of time. In other words, how certain proteins present in immune system cells change in expression and therefore, in function, leading to changes in the function of immune system cells. We are mainly focused on analyzing the cells of the innate immune system corresponding to macrophages. We are interested in understanding how these changes in protein levels lead to pathologies in different systems such as the central nervous system and its effect on neurodegeneration and tissue regeneration, as well as the metabolic changes that occur systemically and in relation to the accumulation of fats.

    Personal profile

    She is researching the aging process and the proteins that can recognize a cell's own mutated DNA or exogenous DNA from viruses and bacteria. These proteins participate in protection against pathogens and also prevent tumor development. However, little is known about their role during aging. In the laboratory where she works, she investigates how these messages change over time and how they could be related to inflammatory diseases that affect metabolism, tissue regeneration, and the development of neurodegeneration.

    Expertise related to UN Sustainable Development Goals

    In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

    • SDG 3 - Good Health and Well-being

    External positions

    Universidad Mayor, Santiago, Chile

    20202021

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