Research output per year
Research output per year
- 50 results
Search results
-
2024
LAT1-dependent placental methionine uptake is a key player in fetal programming of metabolic disease
Schroeder, M., Fuenzalida, B., Yi, N., Shahnawaz, S., Gertsch, J., Pellegata, D., Ontsouka, E., Leiva, A., Gutiérrez, J., Müller, M., Brocco, M. A. & Albrecht, C., 2024, In: Metabolism. 153, 155793.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
2023
A Mouse Systems Genetics Approach Reveals Common and Uncommon Genetic Modifiers of Hepatic Lysosomal Enzyme Activities and Glycosphingolipids
Durán, A., Priestman, D. A., Las Heras, M., Rebolledo-Jaramillo, B., Olguín, V., Calderón, J. F., Zanlungo, S., Gutiérrez, J., Platt, F. M. & Klein, A. D., 2023, In: International Journal of Molecular Sciences. 24, 5, 4915.Research output: Contribution to journal › Article › peer-review
Open Access1 Scopus citations -
An mHealth Intervention to Reduce Gestational Obesity (mami-educ): Protocol for a Randomized Controlled Trial
Chiarello, D. I., Pardo, F., Moya, J., Pino, M., Rodríguez, A., Araneda, M. E., Bertini, A. & Gutiérrez, J., 2023, In: JMIR Research Protocols. 12, e44456.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Cellular mechanisms linking to outdoor and indoor air pollution damage during pregnancy
Chiarello, D. I., Ustáriz, J., Marín, R., Carrasco-Wong, I., Farías, M., Giordano, A., Gallardo, F. S., Illanes, S. E. & Gutiérrez, J., 2023, In: Frontiers in Endocrinology. 14, 1084986.Research output: Contribution to journal › Review article › peer-review
Open Access14 Scopus citations -
Small extracellular vesicles from pregnant women with maternal supraphysiological hypercholesterolemia impair endothelial cell function in vitro
Contreras-Duarte, S., Escalona-Rivano, R., Cantin, C., Valdivia, P., Zapata, D., Carvajal, L., Brito, R., Cerda, Á., Illanes, S., Gutiérrez, J. & Leiva, A., 2023, In: Vascular Pharmacology. 150, 107174.Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
2022
Evaluation of the PLAC8 Gene in Mexican Women With and Without Preeclampsia and Obesity
Barragán-Zúñiga, L. J., Marchat, L. A., Carrasco-Wong, I., Blanco-Castaneda, R., Salas-Pacheco, J. M., Simental-Mendia, L. E., Correa-Ramírez, M. M., Sosa-Macías, M., Gutiérrez, J. & Galaviz-Hernandez, C., 2022, In: Frontiers in Medicine. 9, 795309.Research output: Contribution to journal › Article › peer-review
Open Access2 Scopus citations -
Increased Circulating Levels of PCSK9 and Pro-Atherogenic Lipoprotein Profile in Pregnant Women with Maternal Supraphysiological Hypercholesterolemia
Cantin, C., Garchitorena, M. J., Carvajal, J. A., Illanes, S. E., Gutierrez, J., Leiva, A. & Escalona Rivano, R. S., 2022, In: Antioxidants. 11, 5, 869.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations -
Pathophysiological Role of Genetic Factors Associated With Gestational Diabetes Mellitus
Ortega-Contreras, B., Armella, A., Appel, J., Mennickent, D., Araya, J., González, M., Castro, E., Obregón, A. M., Lamperti, L., Gutiérrez, J. & Guzmán-Gutiérrez, E., 2022, In: Frontiers in Physiology. 13, 769924.Research output: Contribution to journal › Review article › peer-review
Open Access12 Scopus citations -
PLAC8 as a determining invasivity and differentiation factor on human trophoblast
Barragán-Zúñiga, L. J., Galaviz-Hernández, C., Gutiérrez, J. & Sosa-Macías, M., 2022, In: Placenta. 122, p. 25Research output: Contribution to journal › Article › peer-review
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Primary Human Trophoblasts Mimic the Preeclampsia Phenotype after Acute Hypoxia–Reoxygenation Insult
Fuenzalida, B., Kallol, S., Zaugg, J., Mueller, M., Mistry, H. D., Gutierrez, J., Leiva, A. & Albrecht, C., 2022, In: Cells. 11, 12, 1898.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
2021
Autophagy Process in Trophoblast Cells Invasion and Differentiation: Similitude and Differences With Cancer Cells
Carvajal, L., Gutiérrez, J., Morselli, E. & Leiva, A., 2021, In: Frontiers in Oncology. 11, 637594.Research output: Contribution to journal › Review article › peer-review
Open Access17 Scopus citations -
Reduced RECK levels accelerate skeletal muscle differentiation, improve muscle regeneration, and decrease fibrosis
Gutiérrez, J., Gonzalez, D., Escalona-Rivano, R., Takahashi, C. & Brandan, E., 2021, In: FASEB Journal. 35, 5, e21503.Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
Syncytiotrophoblast stress in early onset preeclampsia: The issues perpetuating the syndrome
Carrasco-Wong, I., Aguilera-Olguín, M., Escalona-Rivano, R., Chiarello, D. I., Barragán-Zúñiga, L. J., Sosa-Macías, M., Galaviz-Hernandez, C., San Martín, S. & Gutiérrez, J., 2021, In: Placenta. 113, p. 57-66 10 p.Research output: Contribution to journal › Article › peer-review
17 Scopus citations -
2020
Cholesterol uptake and efflux are impaired in human trophoblast cells from pregnancies with maternal supraphysiological hypercholesterolemia
Fuenzalida, B., Cantin, C., Kallol, S., Carvajal, L., Pastén, V., Contreras-Duarte, S., Albrecht, C., Gutierrez, J. & Leiva, A., 2020, In: Scientific Reports. 10, 1, 5264.Research output: Contribution to journal › Article › peer-review
Open Access35 Scopus citations -
Role of proteases in dysfunctional placental vascular remodelling in preeclampsia
Gutiérrez, J. A., Gómez, I., Chiarello, D. I., Salsoso, R., Klein, A. D., Guzmán-Gutiérrez, E., Toledo, F. & Sobrevia, L., 2020, In: Biochimica et Biophysica Acta - Molecular Basis of Disease. 1866, 2, 165448.Research output: Contribution to journal › Review article › peer-review
Open Access14 Scopus citations -
2018
Maternal supraphysiological hypercholesterolemia associates with endothelial dysfunction of the placental microvasculature
Fuenzalida, B., Sobrevia, B., Cantin, C., Carvajal, L., Salsoso, R., Gutiérrez, J., Contreras-Duarte, S., Sobrevia, L. & Leiva, A., 2018, In: Scientific Reports. 8, 1, 7690.Research output: Contribution to journal › Article › peer-review
Open Access32 Scopus citations -
Mechanisms of the effect of magnesium salts in preeclampsia
Chiarello, D. I., Marín, R., Proverbio, F., Coronado, P., Toledo, F., Salsoso, R., Gutiérrez, J. & Sobrevia, L., 2018, In: Placenta. 69, p. 134-139 6 p.Research output: Contribution to journal › Article › peer-review
22 Scopus citations -
Role of extracellular vesicles in glioma progression
Quezada, C., Torres, Á., Niechi, I., Uribe, D., Contreras-Duarte, S., Toledo, F., San Martín, R., Gutiérrez, J. & Sobrevia, L., 2018, In: Molecular Aspects of Medicine. 60, p. 38-51 14 p.Research output: Contribution to journal › Review article › peer-review
67 Scopus citations -
2017
Adenosine and preeclampsia
Salsoso, R., Farías, M., Gutiérrez, J., Pardo, F., Chiarello, D. I., Toledo, F., Leiva, A., Mate, A., Vázquez, C. M. & Sobrevia, L., 2017, In: Molecular Aspects of Medicine. 55, p. 126-139 14 p.Research output: Contribution to journal › Review article › peer-review
47 Scopus citations -
Adenosine receptors: Modulators of lipid availability that are controlled by lipid levels
Leiva, A., Guzmán-Gutiérrez, E., Contreras-Duarte, S., Fuenzalida, B., Cantin, C., Carvajal, L., Salsoso, R., Gutiérrez, J., Pardo, F. & Sobrevia, L., 2017, In: Molecular Aspects of Medicine. 55, p. 26-44 19 p.Research output: Contribution to journal › Review article › peer-review
36 Scopus citations -
Cross talk between adipose tissue and placenta in obese and gestational diabetes mellitus pregnancies via exosomes
Jayabalan, N., Nair, S., Nuzhat, Z., Rice, G. E., Zuñiga, F. A., Sobrevia, L., Leiva, A., Sanhueza, C., Gutiérrez, J. A., Lappas, M., Freeman, D. J. & Salomon, C., 2017, In: Frontiers in Endocrinology. 8, SEP, 239.Research output: Contribution to journal › Review article › peer-review
Open Access88 Scopus citations -
Molecular implications of adenosine in obesity
Pardo, F., Villalobos-Labra, R., Chiarello, D. I., Salsoso, R., Toledo, F., Gutierrez, J., Leiva, A. & Sobrevia, L., 2017, In: Molecular Aspects of Medicine. 55, p. 90-101 12 p.Research output: Contribution to journal › Review article › peer-review
46 Scopus citations -
Preeclampsia associates with RECK-dependent decrease in human trophoblasts migration and invasion
Gutiérrez, J., Aedo, A., Mora, J., Maldonado, J., Salsoso, R., Toledo, F., Farías, M., Pardo, F., Leiva, A. & Sobrevia, L., 2017, In: Placenta. 59, p. 19-29 11 p.Research output: Contribution to journal › Article › peer-review
15 Scopus citations -
Sodium/proton exchanger isoform 1 regulates intracellular pH and cell proliferation in human ovarian cancer
Sanhueza, C., Araos, J., Naranjo, L., Toledo, F., Beltrán, A. R., Ramírez, M. A., Gutiérrez, J., Pardo, F., Leiva, A. & Sobrevia, L., 2017, In: Biochimica et Biophysica Acta - Molecular Basis of Disease. 1863, 1, p. 81-91 11 p.Research output: Contribution to journal › Article › peer-review
Open Access27 Scopus citations -
2016
A hypothesis for the role of RECK in angiogenesis
Gutiérrez, J., Droppelmann, C. A., Salsoso, R., Westermeier, F., Toledo, F., Salomon, C., Sanhueza, C., Pardo, F., Leiva, A. & Sobrevia, L., 2016, In: Current Vascular Pharmacology. 14, 1, p. 106-115 10 p.Research output: Contribution to journal › Article › peer-review
22 Scopus citations -
Are NHE1 and inducible nitric oxide synthase involved in human ovarian cancer?
Sanhueza, C., Araos, J., Naranjo, L., Barros, E., Toledo, L., Subiabre, M., Toledo, F., Gutiérrez, J., Chiarello, D. I., Pardo, F., Leiva, A. & Sobrevia, L., 2016, In: Pharmacological Research. 105, p. 183-185 3 p.Research output: Contribution to journal › Letter › peer-review
5 Scopus citations -
Insulin is a key modulator of fetoplacental endothelium metabolic disturbances in gestational diabetes mellitus
Sobrevia, L., Salsoso, R., Fuenzalida, B., Barros, E., Toledo, L., Silva, L., Pizarro, C., Subiabre, M., Villalobos, R., Araos, J., Toledo, F., González, M., Gutiérrez, J., Farías, M., Chiarello, D. I., Pardo, F. & Leiva, A., 2016, In: Frontiers in Physiology. 7, MAR, 119.Research output: Contribution to journal › Review article › peer-review
Open Access47 Scopus citations -
Insulin receptor isoforms: An integrated view focused on gestational diabetes mellitus
Westermeier, F., Sáez, T., Arroyo, P., Toledo, F., Gutiérrez, J., Sanhueza, C., Pardo, F., Leiva, A. & Sobrevia, L., 2016, In: Diabetes/Metabolism Research and Reviews. 32, 4, p. 350-365 16 p.Research output: Contribution to journal › Review article › peer-review
Open Access37 Scopus citations -
Intracellular and extracellular pH dynamics in the human placenta from diabetes mellitus
Araos, J., Silva, L., Salsoso, R., Sáez, T., Barros, E., Toledo, F., Gutiérrez, J., Pardo, F., Leiva, A., Sanhueza, C. & Sobrevia, L., 2016, In: Placenta. 43, p. 47-53 7 p.Research output: Contribution to journal › Article › peer-review
13 Scopus citations -
Modulation of intracellular ph in human ovarian cancer
Sanhueza, C., Araos, J., Naranjo, L., Villalobos, R., Westermeier, F., Salomon, C., Beltrán, A. R., Ramirez, M. A., Gutierrez, J., Pardo, F., Leiva, A. & Sobrevia, L., 2016, In: Current Molecular Medicine. 16, 1, p. 23-32 10 p.Research output: Contribution to journal › Article › peer-review
14 Scopus citations -
Nitric oxide and pH modulation in gynaecological cancer
Sanhueza, C., Araos, J., Naranjo, L., Barros, E., Subiabre, M., Toledo, F., Gutiérrez, J., Chiarello, D. I., Pardo, F., Leiva, A. & Sobrevia, L., 2016, In: Journal of Cellular and Molecular Medicine. 20, 12, p. 2223-2230 8 p.Research output: Contribution to journal › Review article › peer-review
Open Access10 Scopus citations -
Nitric oxide is a central common metabolite in vascular dysfunction associated with diseases of human pregnancy
Leiva, A., Fuenzalida, B., Barros, E., Sobrevia, B., Salsoso, R., Sáez, T., Villalobos, R., Silva, L., Chiarello, I., Toledo, F., Gutiérrez, J., Sanhueza, C., Pardo, F. & Sobrevia, L., 2016, In: Current Vascular Pharmacology. 14, 3, p. 237-259 23 p.Research output: Contribution to journal › Article › peer-review
36 Scopus citations -
Observations of the effect of a New Year’s fireworks display on the behavior of the South American sea lion (Otaria flavescens) in a colony of central-south Chile
Pedreros, E., Sepúlveda, M., Gutierrez, J., Carrasco, P. & Quiñones, R. A., 2016, In: Marine and Freshwater Behaviour and Physiology. 49, 2, p. 127-131 5 p.Research output: Contribution to journal › Article › peer-review
4 Scopus citations -
Role for tetrahydrobiopterin in the fetoplacental endothelial dysfunction in maternal supraphysiological hypercholesterolemia
Leiva, A., Fuenzalida, B., Westermeier, F., Toledo, F., Salomón, C., Gutiérrez, J., Sanhueza, C., Pardo, F. & Sobrevia, L., 2016, In: Oxidative Medicine and Cellular Longevity. 2016, 5346327.Research output: Contribution to journal › Review article › peer-review
Open Access11 Scopus citations -
Tetrahydrobiopterin Role in human umbilical vein endothelial dysfunction in maternal supraphysiological hypercholesterolemia
Leiva, A., Fuenzalida, B., Salsoso, R., Barros, E., Toledo, F., Gutiérrez, J., Pardo, F. & Sobrevia, L., 2016, In: Biochimica et Biophysica Acta - Molecular Basis of Disease. 1862, 4, p. 536-544 9 p.Research output: Contribution to journal › Article › peer-review
Open Access20 Scopus citations -
2015
Human supraphysiological gestational weight gain and fetoplacental vascular dysfunction
Pardo, F., Silva, L., Sáez, T., Salsoso, R., Gutiérrez, J., Sanhueza, C., Leiva, A. & Sobrevia, L., 2015, In: International Journal of Obesity. 39, 8, p. 1264-1273 10 p.Research output: Contribution to journal › Article › peer-review
Open Access35 Scopus citations -
Mesenchymal stem cell therapy for doxorubicin cardiomyopathy: Hopes and fears
Ezquer, F., Gutiérrez, J., Ezquer, M., Caglevic, C., Salgado, H. C. & Calligaris, S. D., 2015, In: Stem Cell Research and Therapy. 6, 1, 116.Research output: Contribution to journal › Review article › peer-review
Open Access20 Scopus citations -
RECK-mediated β1-integrin regulation by TGF-β1 is critical for wound contraction in mice
Gutiérrez, J., Droppelmann, C. A., Contreras, O., Takahashi, C. & Brandan, E., 2015, In: PLoS ONE. 10, 8, e0135005.Research output: Contribution to journal › Article › peer-review
Open Access11 Scopus citations -
2014
Andrographolide attenuates skeletal muscle dystrophy in mdx mice and increases efficiency of cell therapy by reducing fibrosis
Cabrera, D., Gutiérrez, J., Cabello-Verrugio, C., Morales, M. G., Mezzano, S., Fadic, R., Casar, J. C., Hancke, J. L. & Brandan, E., 2014, In: Skeletal Muscle. 4, 1, 6.Research output: Contribution to journal › Article › peer-review
Open Access37 Scopus citations -
Glypican-1 regulates myoblast response to HGF via Met in a lipid raft-dependent mechanism: Effect on migration of skeletal muscle precursor cells
Gutiérrez, J., Cabrera, D. & Brandan, E., 2014, In: Skeletal Muscle. 4, 1, 5.Research output: Contribution to journal › Article › peer-review
Open Access28 Scopus citations -
Novel and optimized strategies for inducing fibrosis in vivo: Focus on Duchenne Muscular Dystrophy
Pessina, P., Cabrera, D., Morales, M. G., Riquelme, C. A., Gutiérrez, J., Serrano, A. L., Brandan, E. & Muñoz-Cánoves, P., 2014, In: Skeletal Muscle. 4, 1, 7.Research output: Contribution to journal › Article › peer-review
Open Access80 Scopus citations -
2013
Mice Long-Term High-Fat Diet Feeding Recapitulates Human Cardiovascular Alterations: An Animal Model to Study the Early Phases of Diabetic Cardiomyopathy
Calligaris, S. D., Lecanda, M., Solis, F., Ezquer, M., Gutiérrez, J., Brandan, E., Leiva, A., Sobrevia, L. & Conget, P., 2013, In: Plos One . 8, 4, e60931.Research output: Contribution to journal › Article › peer-review
Open Access129 Scopus citations -
Reducing CTGF/CCN2 slows down mdx muscle dystrophy and improves cell therapy
Morales, M. G., Gutierrez, J., Cabello-Verrugio, C., Cabrera, D., Lipson, K. E., Goldschmeding, R. & Brandan, E., 2013, In: Human Molecular Genetics. 22, 24, p. 4938-4951 14 p., ddt352.Research output: Contribution to journal › Article › peer-review
Open Access121 Scopus citations -
Role of proteoglycans in the regulation of the skeletal muscle fibrotic response
Brandan, E. & Gutierrez, J., 2013, In: FEBS Journal. 280, 17, p. 4109-4117 9 p.Research output: Contribution to journal › Review article › peer-review
Open Access38 Scopus citations -
Role of skeletal muscle proteoglycans during myogenesis
Brandan, E. & Gutierrez, J., 2013, In: Matrix Biology. 32, 6, p. 289-297 9 p.Research output: Contribution to journal › Short survey › peer-review
Open Access60 Scopus citations -
2011
Decorin interacts with connective tissue growth factor (CTGF)/CCN2 by LRR12 inhibiting its biological activity
Vial, C., Gutiérrez, J., Santander, C., Cabrera, D. & Brandan, E., 2011, In: Journal of Biological Chemistry. 286, 27, p. 24242-24252 11 p.Research output: Contribution to journal › Article › peer-review
Open Access95 Scopus citations -
2010
A novel mechanism of sequestering fibroblast growth factor 2 by glypican in lipid rafts, allowing skeletal muscle differentiation
Gutiérrez, J. & Brandan, E., 2010, In: Molecular and Cellular Biology. 30, 7, p. 1634-1649 16 p.Research output: Contribution to journal › Article › peer-review
Open Access96 Scopus citations -
2009
Matrix metalloproteinase-2-deficient fibroblasts exhibit an alteration in the fibrotic response to connective tissue growth factor/CCN2 because of an increase in the levels of endogenous fibronectin
Droppelmann, C. A., Gutiérrez, J., Vial, C. & Brandan, E., 2009, In: Journal of Biological Chemistry. 284, 20, p. 13551-13561 11 p.Research output: Contribution to journal › Article › peer-review
Open Access34 Scopus citations -
2006
Changes in secreted and cell associated proteoglycan synthesis during conversion of myoblasts to osteoblasts in response to bone morphogenetic protein-2: Role of decorin in cell response to BMP-2
Gutierrez, J., Osses, N. & Brandan, E., 2006, In: Journal of Cellular Physiology. 206, 1, p. 58-67 10 p.Research output: Contribution to journal › Article › peer-review
41 Scopus citations -
Sulfation is required for bone morphogenetic protein 2-dependent Id1 induction
Osses, N., Gutierrez, J., Lopez-Rovira, T., Ventura, F. & Brandan, E., 2006, In: Biochemical and Biophysical Research Communications. 344, 4, p. 1207-1215 9 p.Research output: Contribution to journal › Article › peer-review
7 Scopus citations