Projects per year
Personal profile
Research interests
His research focuses on the intracellular trafficking of the epidermal growth factor receptor (EGFR) by ligand-independent mechanisms, as well as the participation of Galectin-8 in signaling in different cell types.
Personal profile
She is a Biochemist and Doctor in Biological Sciences, Cellular and Molecular Biology from the Pontifical Catholic University of Chile.
Teaching
At the Faculty of Medicine and Science, he teaches classes on Basics of Immunology, Professional Practice, Molecular Biology, Molecular Biology Laboratory, Molecular Microbiology and Radiochemistry Laboratory and Biosafety
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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FONDECYT R-1221028: The impact of age-associated changes in TGFbeta signalling on neuron-microglia interaction and its implication for neurodegenerative diseases
Von Bernhardi Montgomery, R. E. (PI), Metz Baer, C. A. (CoI) & León, J. E. (CoI)
01/04/22 → 31/03/26
Project: Research
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FONDECYT R-1181907: PKA-mediated regulation of EGFR endocytic trafficking: Molecular mechanisms and functional implications
González De La Rosa, L. A. (PI), Soza Gajardo, A. M. (CoI), Retamal Villarroel, C. E. (CoI) & Metz Baer, C. A. (CoI)
Agencia Nacional de Investigaci?n y Desarrollo
01/04/18 → 01/04/22
Project: PROYECTO DE INVESTIGACIÓN
Research output
- 16 Article
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D-propranolol impairs egfr trafficking and destabilizes mutant p53 counteracting akt signaling and tumor malignancy
Barra, J., Cerda-Infante, J., Sandoval, L., Gajardo-Meneses, P., Henriquez, J. F., Labarca, M., Metz, C., Venegas, J., Retamal, C., Oyanadel, C., Cancino, J., Soza, A., Cuello, M. A., Roa, J. C., Montecinos, V. P. & Gonzalez, A., 2021, In: Cancers. 13, 14, 3622.Research output: Contribution to journal › Article › peer-review
Open Access6 Scopus citations -
Phosphatidic acid-PKA signaling regulates p38 and ERK1/2 functions in ligand-independent EGFR endocytosis
Metz, C., Oyanadel, C., Jung, J., Retamal, C., Cancino, J., Barra, J., Venegas, J., Du, G., Soza, A. & González, A., 2021, In: Traffic. 22, 10, p. 345-361 17 p.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations -
Galectin-8 mediates fibrogenesis induced by cyclosporine in human gingival fibroblasts
Smith, P. C., Metz, C., de la Peña, A., Oyanadel, C., Avila, P., Arancibia, R., Vicuña, L., Retamal, C., Barake, F., González, A. & Soza, A., 2020, In: Journal of Periodontal Research. 55, 5, p. 724-733 10 p.Research output: Contribution to journal › Article › peer-review
5 Scopus citations -
GALECTIN-8 Is a Neuroprotective Factor in the Brain that Can Be Neutralized by Human Autoantibodies
Pardo, E., Barake, F., Godoy, J. A., Oyanadel, C., Espinoza, S., Metz, C., Retamal, C., Massardo, L., Tapia-Rojas, C., Inestrosa, N. C., Soza, A. & González, A., 2019, In: Molecular Neurobiology. 56, 11, p. 7774-7788 15 p.Research output: Contribution to journal › Article › peer-review
24 Scopus citations -
Galectin-8 induces partial epithelial–mesenchymal transition with invasive tumorigenic capabilities involving a FAK/EGFR/proteasome pathway in Madin–Darby canine kidney cells
Oyanadel, C., Holmes, C., Pardo, E., Retamal, C., Shaughnessy, R., Smith, P., Cortés, P., Bravo-Zehnder, M., Metz, C., Feuerhake, T., Romero, D. V., Roa, J. C., Montecinos, V., Soza, A. & Gonzáleza, A., 2018, In: Molecular Biology of the Cell. 29, 5, p. 557-574 18 p.Research output: Contribution to journal › Article › peer-review
Open Access30 Scopus citations