Projects per year
Personal profile
Research interests
Currently his research focuses on the combination of structural bioinformatics tools with modern organic synthesis methods and advanced cellular and molecular biology techniques, for the identification and development of new bioactive molecules for the treatment of neurodegenerative, metabolic and infectious diseases. In the last 10 years, he has participated as principal investigator and co-director of a CORFO Project and co-investigator of FONDECYT projects. His research has generated 57 indexed publications, several PCT patent applications, and presentations at national and international conferences. At the national level, it collaborates with researchers from the University of Chile and the Catholic University. At an international level, he collaborates with the University College of London and the Institute Pasteur of France.
Personal profile
Dr. Carlos F. Lagos obtained his degree in Pharmaceutical Chemist from the Pontificia Universidad Católica de Chile in 2008, and later in 2016 he obtained a doctorate in Biotechnology from the Andrés Bello University (Santiago, Chile). Before joining the Universidad San Sebastián, he was an assistant professor in the Department of Endocrinology of the School of Medicine of the P. Universidad Católica de Chile. He is currently principal investigator of the Laboratory of Biological Chemistry and Drug Discovery and professor of Pharmacochemistry at the School of Chemistry and Pharmacy, Faculty of Medicine and Science.
Teaching
Academic Core Professor Doctoral Program in Computational Biology, Faculty of Engineering and Architecture, Universidad San Sebastián, Santiago, Chile, 2021-to date.
Collaborating Professor Doctoral Program in Bioinformatics and Systems Biology, Faculty of Life Sciences, Universidad Andrés Bello, Santiago, Chile, 2020-to date.
Academic Core Professor, Master's Program in Molecular Biomedicine, Faculty of Medicine and Science, San Sebastián University, Santiago, Chile, 2018-to date.
Collaborating Professor Doctoral Program in Cellular Biology and Biomedicine, Faculty of Medicine and Science, Universidad San Sebastián, Santiago, Chile, 2018-to date.
Associate Professor, Professional Courses Pharmacochemistry I and II, Chemistry and Pharmacy Career, Faculty of Medicine and Science, San Sebastián University, Santiago, Chile, 2013-to date.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
External positions
Pontificia Universidad Católica de Chile
2014 → 2018
Pontificia Universidad Católica de Chile
2011 → 2014
Pontificia Universidad Católica de Chile
2009 → 2011
Pontificia Universidad Católica de Chile
2007 → 2009
Cargo USS
- Docente Investigador (a)
Jerarquía Académica
- Profesor Asociado
Línea de Investigación
- Línea de Investigación
Macrodisciplinas
- Macrodisciplinas
Disciplinas ANID
- Disciplinas
Fingerprint
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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FONDEF-ID25I10016: NOVEDOSA APROXIMACIÓN PARA EL TRATAMIENTO CONTRA LA FIBROSIS: DESARROLLO Y EVALUACIÓN DE NUEVOS PÉPTIDOS INHIBIDORES DEL FACTOR DE CRECIMIENTO PRO-FIBRÓTICO DE TEJIDO CONECTIVO (CTGF)
Brandan Siques, E. H. (Director(a)), Araya Secchi, R. R. (Deputy director), Lagos Arevalo, C. F. (Investigador(a)), Martínez Fuenzalida, Á. (Investigador(a)) & Faúndez Contreras, J. V. (Investigador(a))
02/07/25 → 01/07/27
Project: PROYECTO DE INVESTIGACIÓN APLICADA
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FONDECYT R-1241969: Targeting the Mineralocorticoid Receptor Activation as a Novel Approach for Obesity and Metabolic Syndrome
Lagos Arevalo, C. F. (Investigador(a) Responsable), Amoroso, A. J. (CoI), Vecchiola, A. (CoI) & Recabarren-Gajardo, G. (CoI)
Agencia Nacional de Investigaci?n y Desarrollo
01/04/24 → 31/03/28
Project: PROYECTO DE INVESTIGACIÓN
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FONDECYT R-1241192: Discovery of Novel Multi Targeted Serotonergic Ligands: An Interdisciplinary Approach towards Candidates directed to Social and Cognitive Symptomathic Domains of Neurodevelopmental Diseases
Lagos Arevalo, C. F. (CoI), Recabarren-Gajardo, G. (Investigador(a) Responsable), Egaña, J. T. (CoI) & Sfeir, A. D. C. (CoI)
Agencia Nacional de Investigaci?n y Desarrollo
01/04/24 → 31/03/28
Project: PROYECTO DE INVESTIGACIÓN
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FONDEQUIP-EQM200058: Mejora del Sistema de Almacenamiento del NLHPC
Lagos Arevalo, C. F. (CoI), San Martín Arístegui, J. R. (CoI), Gallardo Klenner, L. L. (CoI), Maass Sepúlveda, A. E. (CoI), Guerrero Hernandez, G. D. (Investigador(a) Responsable) & Ortega, J. (CoI)
Agencia Nacional de Investigaci?n y Desarrollo
01/01/21 → 30/06/24
Project: PROYECTO DE EQUIPAMIENTO
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FONDECYT R-1160695: Aldosterone dysregulation in metabolic syndrome, obesity and inflammation: Clinical and in vitro studies
Lagos Arevalo, C. F. (CoI) & Fardella, C. E. (Investigador(a) Responsable)
Agencia Nacional de Investigaci?n y Desarrollo
02/05/18 → 01/04/20
Project: PROYECTO DE INVESTIGACIÓN
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A complex multisystem disorder including hypopituitarism and hypoparathyroidism, associated with mutation in the gene encoding fatty acid synthase (FASN)
Gregory, L. C., Krywawych, S., Rahman, S., Lagos, C. F., Eaton, S. & Dattani, M. T., 2025, In: Metabolism. 168, 156256.Research output: Contribution to journal › Article › peer-review
Open Access -
Influence of an Antioxidant Nanomaterial on Oral Tablet Formulation Flow Properties and Critical Quality Attributes
Ortiz, A. C., Carrasco-Rojas, J., Peñaloza, S., Simirgiotis, M. J., Rubio-Quiroz, L., Ruiz, D., Lagos, C. F., Morales, J. & Arriagada, F., 2025, In: Antioxidants. 14, 7, 829.Research output: Contribution to journal › Article › peer-review
Open Access -
NLC-Based Rifampicin Delivery System: Development and Characterization for Improved Drug Performance Against Staphylococcus aureus
Carrasco-Rojas, J., Sandoval, F. I., Schuh, C. M. A. P., Lagos, C. F., Morales, J. O., Arriagada, F. & Ortiz, A. C., 2025, In: Pharmaceutics. 17, 6, 799.Research output: Contribution to journal › Article › peer-review
Open AccessFile2 Scopus citations3 Downloads (Pure) -
Novel 5-HT6R modulators as mTOR-dependent neuronal autophagy inductors
Alcaíno, J. M., Vera, G., Almarza, G., Lagos, C. F., Terraza, C. A., del Campo, A. & Recabarren-Gajardo, G., 2025, In: Scientific Reports. 15, 1, 13 p., 8380.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Downloads (Pure) -
A conserved NR5A1-responsive enhancer regulates SRY in testis-determination
Houzelstein, D., Eozenou, C., Lagos, C. F., Elzaiat, M., Bignon-Topalovic, J., Gonzalez, I., Laville, V., Schlick, L., Wankanit, S., Madon, P., Kirtane, J., Athalye, A., Buonocore, F., Bigou, S., Conway, G. S., Bohl, D., Achermann, J. C., Bashamboo, A. & McElreavey, K., 2024, In: Nature Communications. 15, 1, 2796.Research output: Contribution to journal › Article › peer-review
Open Access5 Scopus citations