Facultad de Ciencias

2025

Anatomical Variants in Pancreatic Irrigation and Their Clinical Considerations for the Pancreatic Approach and Surrounding Structures: A Systematic Review with Meta-Analysis

Valenzuela-Fuenzalida, J. J., Núñez-Castro, C. I., Morán-Durán, V. B., Nova-Baeza, P., Orellana-Donoso, M., Suazo-Santibáñez, A., Becerra-Farfan, A., Oyanedel-Amaro, G., Bruna-Mejias, A., Granite, G., Casanova-Martinez, D. & Sanchis-Gimeno, J., 2025, In: Medicina (Lithuania). 61, 4, 666.

Research output: Contribution to journal › Review article › peer-review

Open Access

A Systematic Review and Meta-Analysis on the Prevalence of Variants in the Pancreaticobiliary Duct Junction and Its Association with Cancer

Riveros Valdés, A. S., Fuenzalida, J. J. V., Beas-Gambi, A., Leiva, J. M., Martínez-Hernández, D., Milos, D., Orellana-Donoso, M., Suazo Santibáñez, A., Bruna Mejias, A., Becerra-Farfan, A., Sanchis-Gimeno, J. A., Gutiérrez-Espinoza, H. & Bastidas-Caldes, C., 2025, In: Biomedicines. 13, 5, p. 1039-1060 21 p., 1039.

Research output: Contribution to journal › Review article › peer-review

Open Access

Clinical Characteristics of Neuropathic Pain and Its Relationship with Cancer in Different Corporal Areas—A Systematic Review

Danés-López, F., Diaz-Palominos, C., Ortiz Domínguez, A., Silva Rodriguez, A., Astorga, C., Martínez-Hernández, D., Valenzuela-Fuenzalida, J. J., Sanchis-Gimeno, J., Nova-Baeza, P., Suazo-Santibáñez, A., Oyanedel-Amaro, G., Orellana-Donoso, M. & Gutiérrez Espinoza, H., 2025, In: Diagnostics. 15, 1, 116.

Research output: Contribution to journal › Review article › peer-review

Open Access

Effects of exergames on rehabilitation outcomes in patients with osteoarthritis. A systematic review

Guede-Rojas, F., Andrades-Torres, B., Aedo-Díaz, N., González-Koppen, C., Muñoz-Fuentes, M., Enríquez-Enríquez, D., Carvajal-Parodi, C., Mendoza, C., Alvarez, C. & Fuentes-Contreras, J., 2025, In: Disability and Rehabilitation. 47, 5, p. 1100-1113 14 p.

Research output: Contribution to journal › Review article › peer-review

4 Scopus citations

Main methods and tools for peptide development based on protein-protein interactions (PPIs).

Baeza, J., Bedoya, M., Cruz, P., Ojeda, P., Adasme-Carreño, F., Cerda, O. & González, W., 2025, In: Biochemical and Biophysical Research Communications. 758, p. 151623 151623.

Research output: Contribution to journal › Review article › peer-review

The Intrinsically Disordered Region of HBx and Virus–Host Interactions: Uncovering New Therapeutic Approaches for HBV and Cancer

Villanueva, R. A. & Loyola, A., 2025, In: International Journal of Molecular Sciences. 26, 8, 3552.

Research output: Contribution to journal › Review article › peer-review

Open Access

1 Scopus citations

“Challenges in the implementation of inter-professional education programs with clinical simulation for health care students: A scoping review“

Chávez-Valenzuela, P., Kappes, M., Sambuceti, C. E. & Díaz-Guio, D. A., 2025, In: Nurse Education Today. 146, 106548.

Research output: Contribution to journal › Review article › peer-review

1 Scopus citations

2024

A comprehensive review of titanium dioxide nanoparticles in cementitious composites

Jenima, J., Priya Dharshini, M., Ajin, M. L., Jebeen Moses, J., Retnam, K. P., Arunachalam, K. P., Avudaiappan, S. & Arrue Munoz, R. F., 2024, In: Heliyon. 10, 20, e39238.

Research output: Contribution to journal › Review article › peer-review

Open Access

7 Scopus citations

Are we cultivating the perfect storm for a human avian influenza pandemic?

Perez-Acle, T., Rosemblatt, M. & Ravello, C., 2024, In: Biological Research. 57, 1, 96.

Research output: Contribution to journal › Review article › peer-review

Open Access

7 Scopus citations

Association between the Anatomical Location of Glioblastoma and Its Evaluation with Clinical Considerations: A Systematic Review and Meta-Analysis

Valenzuela-Fuenzalida, J. J., Moyano-Valarezo, L., Silva-Bravo, V., Milos-Brandenberg, D., Orellana-Donoso, M., Nova-Baeza, P., Suazo-Santibáñez, A., Rodríguez-Luengo, M., Oyanedel-Amaro, G., Sanchis-Gimeno, J. & Gutiérrez Espinoza, H., 2024, In: Journal of Clinical Medicine. 13, 12, p. 2 61 p., 3460.

Research output: Contribution to journal › Review article › peer-review

Open Access

5 Scopus citations

Biological role of fructose in the male reproductive system: Potential implications for prostate cancer

Echeverría, C. E., Oyarzún, V. I., López-Cortés, A., Cancino, J., Sotomayor, P. C., Goncalves, M. D. & Godoy, A. S., 2024, In: Prostate. 84, 1, p. 8-24 17 p.

Research output: Contribution to journal › Review article › peer-review

8 Scopus citations

Clasificación de Rosemont para pancreatitis crónica

Arenas Delgado, J. W., Segovia Vergara, E. A., Sanchez Montes, C. & Mansilla Vivar, R. A., 2024, In: Gastroenterología Latinoamericana. 35, 1, p. 27-31

Research output: Contribution to journal › Review article › peer-review

Open Access

Comprehensive Gerontological Assessment: An Update on the Concept and Its Evaluation Tools in Latin America and the Caribbean—A Literature Review

Pizarro-Mena, R., Rotarou, E. S., Chavarro-Carvajal, D., Wachholz, P. A., López, M. F., Delgado, C. P., Parra-Soto, S., Barrientos-Calvo, I., Retamal-Walter, F. & Riveros-Basoalto, G., 2024, In: International Journal of Environmental Research and Public Health. 21, 12, 1697.

Research output: Contribution to journal › Review article › peer-review

Open Access

1 Scopus citations

Current Research on Molecular Biomarkers for Colorectal Cancer in Stool Samples

Órdenes , P., Carril Pardo, C., Elizondo-Vega, R. & Oyarce, K., 2024, In: Biology. 13, 1, 15.

Research output: Contribution to journal › Review article › peer-review

Open Access

6 Scopus citations

Differential scanning calorimetry in drug-membrane interactions

Zambrano, P., Manrique-Moreno, M., Petit, K., Colina, J. R., Jemiola-Rzeminska, M., Suwalsky, M. & Strzalka, K., 2024, In: Biochemical and Biophysical Research Communications. 709, 149806.

Research output: Contribution to journal › Review article › peer-review

Open Access

5 Scopus citations

Effect of strength training on knee proprioception in patients with knee osteoarthritis. A systematic review and meta-analysis

Guede-Rojas, F., Benavides-Villanueva, A., Salgado-González, S., Mendoza, C., Arias-Álvarez, G., Soto-Martínez, A. & Carvajal-Parodi, C., 2024, In: Sports Medicine and Health Science. 6, 2, p. 101-110 10 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

3 Scopus citations

Galantamine-Memantine Combination in the Treatment of Parkinson’s Disease Dementia

Frost, E. D., Shi, S. X., Byroju, V. V., Pitton Rissardo, J., Donlon, J., Vigilante, N., Murray, B. P., Walker, I. M., McGarry, A., Ferraro, T. N., Hanafy, K. A., Echeverria, V., Mitrev, L., Kling, M. A., Krishnaiah, B., Lovejoy, D. B., Rahman, S., Stone, T. W. & Koola, M. M., 2024, In: Brain Sciences. 14, 12, 1163.

Research output: Contribution to journal › Review article › peer-review

1 Scopus citations

Galectins in epithelial-mesenchymal transition: roles and mechanisms contributing to tissue repair, fibrosis and cancer metastasis

Perez-Moreno, E., Oyanadel, C., de la Peña, A., Hernández, R., Pérez-Molina, F., Metz, C., González, A. & Soza, A., 2024, In: Biological Research. 57, 1, 14.

Research output: Contribution to journal › Review article › peer-review

Open Access

7 Scopus citations

Hepatic Hilum Variations and Their Clinical Considerations in the Liver: A Systematic Review and Meta-Analysis

Valenzuela-Fuenzalida, J. J., Pena-Santibañez, F., Vergara Salinas, A., Meneses Caroca, T., Rojo-Gonzalez, J., Orellana-Donoso, M. I., Nova-Baeza, P., Suazo-Santibañez, A., Sanchis-Gimeno, J. & Gutierrez-Espinoza, H., 2024, In: Life. 14, 10, 1301.

Research output: Contribution to journal › Review article › peer-review

Open Access

1 Scopus citations

Hypoplastic and Congenital Absence of Coronary Arteries and Its Correlation with Clinical Implications of Cardiac Circulation: A Systematic Review and Meta-Analysis

Bruna-Mejias, A., del Villar-Valdebenito, J., Roman, C., Alcaíno-Adasme, C., Sepulveda-Loyola, W., Orellana-Donoso, M., Nova-Baeza, P., Suazo-Santibañez, A., Becerra-Farfan, A., Sanchis-Gimeno, J. & Valenzuela-Fuenzalida, J. J., 2024, In: Journal of Clinical Medicine. 13, 11, 3085.

Research output: Contribution to journal › Review article › peer-review

Open Access

Hypothalamic obesity from basic mechanisms to clinical perspectives

Argente, J., Farooqi, I. S., Chowen, J. A., Kühnen, P., López, M., Morselli, E., Gan, H. W., Spoudeas, H. A., Wabitsch, M. & Tena-Sempere, M., 2024, In: The Lancet Diabetes and Endocrinology. 13, 1, p. 57-68 12 p.

Research output: Contribution to journal › Review article › peer-review

3 Scopus citations

KINESIOPHOBIA AS A FACTOR OF RETURN TO SPORT IN PATIENTS UNDERGOING ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION: A SYSTEMATIZED REVIEW

Mendoza Sepúlveda, C. A., Carvajal Parodi, C. J., Riveros Valdés, A. S., Cea Lagos, P., Mendoza Guzmán, H., Urbina Lagos, P. & Guede Rojas, F., 2024, In: Journal of Sport and Health Research. 16, 1, p. 19-38 20 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

Precordial catch syndrome: literature review

Segovia Vergara, E. A., 2024, In: Revista Medica Clinica Las Condes. 35, 2, p. 140-144 5 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

Regulation of Pain Perception by Microbiota in Parkinson Disease

Manjarres, Z., Calvo, M. & Pacheco, R., 2024, In: Pharmacological Reviews. 76, 1, p. 7-36 30 p.

Research output: Contribution to journal › Review article › peer-review

9 Scopus citations

Risk Factors for Ovarian Cancer in South America: A Literature Review

Jara Rosales, S. F., Rotarou, E. S., Villarroel-Espíndola, F. & González-Stegmaier , R., 2024, In: Journal of Personalized Medicine. 14, 9, p. 992 16 p., 992.

Research output: Contribution to journal › Review article › peer-review

Open Access

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3 Scopus citations

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Second victim phenomenon among healthcare students: A scoping review

Catalán, L., Alvarado-Peña, J., Torres-Soto, G., Lorca-Sepúlveda, B., Besoain-Cornejo, A. M. & Kappes, M., 2024, In: Nurse Education in Practice. 79, August 2024, 104094.

Research output: Contribution to journal › Review article › peer-review

1 Scopus citations

Synaptic mitochondria: A crucial factor in the aged hippocampus

Cicali, K. A. & Tapia-Rojas, C., 2024, In: Ageing Research Reviews. 101, 102524.

Research output: Contribution to journal › Review article › peer-review

4 Scopus citations

Systematic Review and Meta-Analysis of Internal Jugular Vein Variants and Their Relationship to Clinical Implications in the Head and Neck

Nova-Baeza, P., Valenzuela-Fuenzalida, J. J., Valdivia-Arroyo, R., Becerra-Rodríguez, E. S., Escalona-Manzo, C., Castaño-Gallego, Y. T., Luque-Bernal, R. M., Oyanedel-Amaro, G., Suazo-Santibáñez, A., Orellana-Donoso, M., Bruna-Mejias, A., Sanchis-Gimeno, J. & Gutiérrez-Espinoza, H., 2024, In: Diagnostics. 14, 23, 2765.

Research output: Contribution to journal › Review article › peer-review

Open Access

1 Scopus citations

The immune system in Parkinson's disease: what we know so far

Cintia, R., Bernardino, L., Oztop-Cakmak, O., Dragic, M., Fladmark, K. E., Ertan, S., Aktas, B., Pita, C., Ciglar, L., Garraux, G., Williams-Gray, C., Pacheco Rivera, R. A. & Romero-Ramos, M., 2024, In: Brain. 147, 10, p. 3306–3324 19 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

27 Scopus citations

The interplay between leptin, glucocorticoids, and GLP1 regulates food intake and feeding behaviour

Perez-Leighton, C., Kerr, B., Scherer, P. E., Baudrand, R. & Cortés, V., 2024, In: Biological Reviews. 99, 3, p. 653-674 22 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

9 Scopus citations

2023

C-Abl kinase at the crossroads of healthy synaptic remodeling and synaptic dysfunction in neurodegenerative diseases

Gutiérrez, D., Chandía-Cristi, A., Yáñez, M., Zanlungo, S. & Álvarez, A., 2023, In: Neural Regeneration Research. 18, 2, p. 237-243 7 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

18 Scopus citations

Cellular mechanisms linking to outdoor and indoor air pollution damage during pregnancy

Chiarello, D. I., Ustáriz, J., Marín, R., Carrasco-Wong, I., Farías, M., Giordano, A., Gallardo, F. S., Illanes, S. E. & Gutiérrez, J., 2023, In: Frontiers in Endocrinology. 14, 1084986.

Research output: Contribution to journal › Review article › peer-review

Open Access

17 Scopus citations

Consideraciones anestésicas en mucopolisacaridosis

Translated title of the contribution: Anesthetic managament in muccipolysaccharidosisAndrés Carmona, L., Luis Alvarez, D., Guillermo López, S. & Marco Balkenhol, N., 2023, In: Revista Chilena de Anestesia. 52, 2, p. 170-176 7 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

Exercise-induced hypoalgesia in chronic neck pain: A narrative review

Rojas-Galleguillos, F., Clark-Hormazábal, C., Méndez-Fuentes, E., Guede-Rojas, F., Riveros Valdés, A., Carvajal-Parodi, C. & Mendoza Sepúlveda, C. A., 2023, In: Sports Medicine and Health Science. 6, 1, p. 37-47 11 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

3 Scopus citations

Exploring the therapeutic potential of the mitochondrial transfer-associated enzymatic machinery in brain degeneration

Luque-Campos, N., Riquelme, R., Molina, L., Canedo-Marroquín, G., Vega-Letter, A. M., Luz-Crawford, P. & Bustamante-Barrientos, F. A., 2023, In: Frontiers in Physiology. 14, 1217815.

Research output: Contribution to journal › Review article › peer-review

Open Access

2 Scopus citations

Metabolic Recruitment in Brain Tissue

Barros, L. F., Ruminot, I., Sotelo-Hitschfeld, T., Lerchundi, R. & Fernández-Moncada, I., 2023, In: Annual review of physiology. 85, p. 115-135 21 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

28 Scopus citations

Mitochondrial dysfunction in neurodegenerative disorders: Potential therapeutic application of mitochondrial transfer to central nervous system-residing cells

Bustamante-Barrientos, F. A., Luque-Campos, N., Araya, M. J., Lara-Barba, E., de Solminihac, J., Pradenas, C., Molina, L., Herrera-Luna, Y., Utreras-Mendoza, Y., Elizondo-Vega, R., Vega-Letter, A. M. & Luz-Crawford, P., 2023, In: Journal of Translational Medicine. 21, 1, 613.

Research output: Contribution to journal › Review article › peer-review

Open Access

71 Scopus citations

On the Chemical and Biological Characteristics of Multifunctional Compounds for the Treatment of Parkinson’s Disease

García-Beltrán, O., Urrutia, P. J. & Núñez, M. T., 2023, In: Antioxidants. 12, 2, 214.

Research output: Contribution to journal › Review article › peer-review

Open Access

13 Scopus citations

Pre- and Post-Transcriptional Control of HBV Gene Expression: The Road Traveled towards the New Paradigm of HBx, Its Isoforms, and Their Diverse Functions

Villanueva, R. A. & Loyola, A., 2023, In: Biomedicines. 11, 6, 1674.

Research output: Contribution to journal › Review article › peer-review

Open Access

3 Scopus citations

Small molecules to perform big roles: The search for Parkinson's and Huntington's disease therapeutics

Pérez-Arancibia, R., Cisternas-Olmedo, M., Sepúlveda, D., Troncoso-Escudero, P. & Vidal, R. L., 2023, In: Frontiers in Neuroscience. 16, 1084493.

Research output: Contribution to journal › Review article › peer-review

Open Access

11 Scopus citations

Subcellular localization and transcriptional regulation of brain ryanodine receptors. Functional implications

Torres, R. & Hidalgo, C., 2023, In: Cell Calcium. 116, 102821.

Research output: Contribution to journal › Review article › peer-review

4 Scopus citations

The WHO European framework for action to achieve the highest attainable standard of health for persons with disabilities 2022–2030

Mishra, S., Rotarou, E. S., Peterson, C. B., Sakellariou, D. & Muscat, N. A., 2023, In: The Lancet Regional Health - Europe. 25, 100555.

Research output: Contribution to journal › Review article › peer-review

Open Access

4 Scopus citations

VIOLENCIA DE GÉNERO EN ESTUDIANTES Y COMUNIDADES UNIVERSITARIAS DEL CONTINENTE AMERICANO: UNA REVISIÓN

Sepulveda Gotterbarm, J. S., Jara Rosales, S. F., Contreras Moreira, V., Diaz Caro, I., Galvez Cáceres, A., González Meza, K., Maldonado Medina, P., Toro Martínez, T. & Vargas Zapata, J., 2023, In: MUSAS. Revista de Investigación en Mujer, Salud y Sociedad. 8, 2, p. 5-23 18 p., DOI: 10.1344/musas2023.vol8.num2.1.

Research output: Contribution to journal › Review article › peer-review

Open Access

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2022

Active Surveillance in Prostate Cancer: Current and Potentially Emerging Biomarkers for Patient Selection Criteria

Sotomayor, P. C., Aguilar, J. C., Mujica, K., Zuñiga, A., Godoy, A. S., Smith, G. J., Mohler, J. L., Vitagliano, G. & San Francisco, I. F., 2022, In: Urologia Internationalis. 106, 12, p. 1201-1213 13 p.

Research output: Contribution to journal › Review article › peer-review

Open Access

9 Scopus citations

Advances in analytical techniques coupled to in vitro bioassays in the search for new peptides with functional activity in effect-directed analysis

Dary Guerra-Fajardo, L., Pavón-Pérez, J., Vallejos-Almirall, A. & Jorquera-Pereira, D., 2022, In: Food Chemistry. 397, 133784.

Research output: Contribution to journal › Review article › peer-review

6 Scopus citations

Autophagy in aging-related oral diseases

Peña-Oyarzún, D., San Martin, C., Hernández-Cáceres, M. P., Lavandero, S., Morselli, E., Budini, M., Burgos, P. V. & Criollo, A., 2022, In: Frontiers in Endocrinology. 13, 903836.

Research output: Contribution to journal › Review article › peer-review

Open Access

8 Scopus citations

Electronic Cigarette Use and the Risk of Cardiovascular Diseases

Espinoza-Derout, J., Shao, X. M., Lao, C. J., Hasan, K. M., Rivera, J. C., Jordan, M. C., Echeverria, V., Roos, K. P., Sinha-Hikim, A. P. & Friedman, T. C., 2022, In: Frontiers in Cardiovascular Medicine. 9, 879726.

Research output: Contribution to journal › Review article › peer-review

Open Access