Projects per year
Organization profile
Organization profile
The PhD Program in Chronic Diseases is based on the growing need for highly trained professionals with the skills to expand the frontiers of knowledge based on research into the pathophysiology of chronic diseases (CD) and, in particular, the study of these diseases in both female and male populations, their relationship with risk factors, aspects associated with their epidemiology and the effect of maternal factors on the programming of these diseases.
Chronic Diseases (CD) are a growing problem worldwide and mainly affect low and middle income countries. According to the World Health Organization (WHO, 2018), together these diseases are responsible for 71% of deaths globally. In our country, about 10 million Chileans have at least one CD. These diseases tend to be long-lasting and result from a combination of genetic, physiological, environmental and behavioral factors.
The program will focus on the development of three main lines of research, which are proposed to be approached from physiological, pathophysiological, epidemiological and clinical aspects, without prejudice that they may be modified according to the evolution of knowledge and the incorporation of new researchers:
- Pathophysiology and epidemiology of chronic diseases.
Risk factors associated with the development of chronic diseases.
Fetal programming of chronic diseases
Organization profile
The PhD Program in Chronic Diseases is based on the growing need for highly trained professionals with the skills to expand the frontiers of knowledge based on research into the pathophysiology of chronic diseases (CD) and, in particular, the study of these diseases in both female and male populations, their relationship with risk factors, aspects associated with their epidemiology and the effect of maternal factors on the programming of these diseases.
Chronic Diseases (CD) are a growing problem worldwide and mainly affect low and middle income countries. According to the World Health Organization (WHO, 2018), together these diseases are responsible for 71% of deaths globally. In our country, about 10 million Chileans have at least one CD. These diseases tend to be long-lasting and result from a combination of genetic, physiological, environmental and behavioral factors.
The program will focus on the development of three main lines of research, which are proposed to be approached from physiological, pathophysiological, epidemiological and clinical aspects, without prejudice that they may be modified according to the evolution of knowledge and the incorporation of new researchers:
- Pathophysiology and epidemiology of chronic diseases.
Risk factors associated with the development of chronic diseases.
Fetal programming of chronic diseases
Keywords
- R Medicine (General)
Fingerprint
Collaborations and top research areas from the last five years
Profiles
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Cristian Alejandro Amador Carrasco, PhD
- Universidad San Sebastián - Investigador
- Facultad de Ciencias - Investigador
- Sede Santiago - Investigador
- Doctorado en Enfermedades Crónicas - Investigador
Person: Researcher
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Carolina Del Carmen Añazco Oyarzún, PhD
- Universidad San Sebastián - Investigador
- Facultad de Ciencias de la Rehabilitación y Calidad de Vida - Investigador
- Sede Valdivia - Investigador
- Magíster en Biomedicina Molecular - Investigador
- Doctorado en Enfermedades Crónicas - Investigador
- Doctorado en Biología Celular y Biomedicina - Investigador
Person: Researcher
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María José Barrera Alvarado, PhD
- Universidad San Sebastián - Investigador
- Facultad de Odontología - Investigador
- Sede Santiago - Investigador
- Magíster en Biomedicina Molecular - Investigador
- Doctorado en Enfermedades Crónicas - Investigador
- Doctorado en Biología Celular y Biomedicina - Investigador
Person: Researcher
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FONDECYT E-13240033: Primary Cilium-Derived Ectosomes: A Novel Mechanism for the Control of Inflammation in the Hypothalamus
Morselli, E. (Investigador(a) Responsable), Varas Godoy, M. A. (Deputy director) & Criollo, A. (CoI)
03/11/24 → 02/11/28
Project: PROYECTO DE INVESTIGACIÓN
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FONDEF-IT24I0064: Automatización de Certificaciones de Miel basada en IA y Cloud Computing para Visualización de datos desde el laboratorio al consumidor
Coelho Caro, P. A. (Investigador(a) Patrocinante), Staforelli Vivanco, J. P. (Investigador(a) Responsable), Rondanelli-Reyes, M. (CoI), Obregón Rivas, A. M. (CoI) & Jara Chávez, A. G. A. (CoI)
01/10/24 → 30/09/26
Project: PROYECTO DE INVESTIGACIÓN APLICADA
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FONDECYT R-1241214: Small extracellular vesicles derived from glycolytic MSC as a new approach to increase neuroprotective role of astrocyte in a murine model of diabetes-induced encephalopathy.
Oyarce Merino, K. A. (CoI), Elizondo-Vega, R. (Investigador(a) Responsable), Luz-Crawford, P. (CoI) & García-Robles, M. D. L. Á. (CoI)
Agencia Nacional de Investigaci?n y Desarrollo
01/04/24 → 31/03/28
Project: PROYECTO DE INVESTIGACIÓN
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A complex multisystem disorder including hypopituitarism and hypoparathyroidism, associated with mutation in the gene encoding fatty acid synthase (FASN)
Gregory, L. C., Krywawych, S., Rahman, S., Lagos, C. F., Eaton, S. & Dattani, M. T., 2025, In: Metabolism. 168, 156256.Research output: Contribution to journal › Article › peer-review
Open Access -
APOE genotype-dependent differences in human astrocytic energy metabolism
Budny, V., Bodenmann, C., Zürcher, K. J., Krüger, M., de Leeuw, S. M., Weber, R. Z., Rust, R., Ravotto, L., Ruminot, I., Barros, L. F., Weber, B. & Tackenberg, C., 2025, In: Frontiers in Cellular Neuroscience. 19, 1603657.Research output: Contribution to journal › Article › peer-review
Open AccessFile1 Downloads (Pure) -
A primary cilia–autophagy axis in hippocampal neurons is essential to maintain cognitive resilience
Rivagorda, M., Romeo-Guitart, D., Blanchet, V., Mailliet, F., Boitez, V., Barry, N., Milunov, D., Siopi, E., Goudin, N., Moriceau, S., Guerrera, C., Leibovici, M., Saha, S., Codogno, P., Morselli, E., Morel, E., Armand, A. S. & Oury, F., 2025, In: Nature Aging. 5, 3, p. 450-467 18 p., 1318.Research output: Contribution to journal › Article › peer-review
Open Access7 Scopus citations
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Neuroendocrine Techniques at the Cutting Edge
Kerr Fuentes, B. D. (Organizer), Belsham, D. (Organizer), Lehman, M. (Organizer), Marshall, C. (Organizer), Evans, N. (Organizer) & Navarro, V. (Organizer)
2023 → 2023Activity: Participating in or organizing an event › Organizing a conference, workshop, ...
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Neuroendocrine Integration of Appetite and Metabolism
Kerr Fuentes, B. D. (Organizer), Navarro, V. (Participant), Scherer, P. E. (Participant), Matus Montero, M. S. (Participant) & Lee Liu, D. N. (Participant)
2023 → 2023Activity: Participating in or organizing an event › Participating in a conference, workshop, ...
Press/Media
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General artificial intelligence and neurobiology advance toward transformative applications in technology and healthcare
Perez Acle, T. O., Morselli, E., Otero Ferreiro, M. & Varas Godoy, M. A.
13/11/24
1 item of Media coverage
Press/Media
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Medicina basada en evidencia: USS inaugura Centro de Investigaciones Clínicas
Vio Lagos, C., Pérez Cortes, C. M., Perez Villarroel, M. L. & Valenzuela Bravo, M. T.
20/03/24
1 Media contribution
Press/Media
Equipment
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Analizador de Imágenes Luminiscentes
Gutiérrez Pérez, J. A. (Manager), Leiva Mendoza, A. A. (Manager), Barrera Alvarado, M. J. (Manager), Contreras Duarte, S. D. L. M. (Manager), Yáñez Henríquez, M. J. (Manager), Morselli, E. (Manager), Chiarello Peñaranda, D. (Manager), Carrasco Wong, I. J. (Manager), Lagos Arevalo, C. F. (Manager), Amador Carrasco, C. A. (Manager) & Vio Lagos, C. (Manager)
Equipment/facility: Equipment
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Autoclave
Lagos Arevalo, C. F. (Operator), Chiarello Peñaranda, D. (Operator), Amador Carrasco, C. A. (Operator), Carrasco Wong, I. J. (Operator), Morselli, E. (Operator), Leiva Mendoza, A. A. (Operator), Barrera Alvarado, M. J. (Operator), Contreras Duarte, S. D. L. M. (Operator), Gutiérrez Pérez, J. A. (Operator), Yáñez Henríquez, M. J. (Operator), Soto Arriaza, M. A. (Operator) & Lee Liu, D. N. (Manager)
Equipment/facility: Equipment
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Campana de Extracción de Gases
Gutiérrez Pérez, J. A. (Operator), Leiva Mendoza, A. A. (Operator), Barrera Alvarado, M. J. (Operator), Contreras Duarte, S. D. L. M. (Operator), Carrasco Wong, I. J. (Operator), Yáñez Henríquez, M. J. (Operator), Soto Arriaza, M. A. (Operator), Chiarello Peñaranda, D. (Operator), Amador Carrasco, C. A. (Operator), Morselli, E. (Operator), Lagos Arevalo, C. F. (Operator), Lee Liu, D. N. (Operator) & Vio Lagos, C. (Manager)
Equipment/facility: Equipment