Projects per year
Organization profile
Organization profile
Computational biology can be defined as a transdisciplinary research field that uses fundamentals from mathematics, physics, chemistry and biology to produce computational models for the study of various biological phenomena. Like any scientific discipline based on data (big data), its advances are strongly linked to the development of computational sciences, particularly in the area of high performance computing (HPC).
Today, computational biology incorporates a variety of fields including, among others, genomics and bioinformatics, molecular modeling and simulation, network theory, machine learning and artificial intelligence, and population dynamics.
The Program places special emphasis on transdisciplinarity, and from this approach seeks to study and provide solutions to problems in the life sciences, social sciences and exact sciences.
In addition to the laboratories of the Science and Life Foundation, it offers the possibility of interacting and carrying out their theses in the research laboratories of some of the biotechnology companies located on our campuses.
During their time in the Program, students will acquire skills that will allow them to identify important questions in the most basic aspects of the disciplines as well as in their medical and environmental applications, formulate and develop research projects, critically read scientific literature, effectively communicate their own findings and ideas, and insert themselves in academia, as well as in the public and private sectors.
The PhD program in Computational Biology is framed within the following lines of research:
- Computational Neuroscience, Data Science and Artificial Intelligence.
- Computational biophysics of macromolecular systems.
- Genomic biology, bioinformatics and biological networks.
Organization profile
Computational biology can be defined as a transdisciplinary research field that uses fundamentals from mathematics, physics, chemistry and biology to produce computational models for the study of various biological phenomena. Like any scientific discipline based on data (big data), its advances are strongly linked to the development of computational sciences, particularly in the area of high performance computing (HPC).
Today, computational biology incorporates a variety of fields including, among others, genomics and bioinformatics, molecular modeling and simulation, network theory, machine learning and artificial intelligence, and population dynamics.
The Program places special emphasis on transdisciplinarity, and from this approach seeks to study and provide solutions to problems in the life sciences, social sciences and exact sciences.
In addition to the laboratories of the Science and Life Foundation, it offers the possibility of interacting and carrying out their theses in the research laboratories of some of the biotechnology companies located on our campuses.
During their time in the Program, students will acquire skills that will allow them to identify important questions in the most basic aspects of the disciplines as well as in their medical and environmental applications, formulate and develop research projects, critically read scientific literature, effectively communicate their own findings and ideas, and insert themselves in academia, as well as in the public and private sectors.
The PhD program in Computational Biology is framed within the following lines of research:
- Computational Neuroscience, Data Science and Artificial Intelligence.
- Computational biophysics of macromolecular systems.
- Genomic biology, bioinformatics and biological networks.
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Collaborations and top research areas from the last five years
Profiles
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Carlos Andrés Aguirre Núñez, PhD
- Universidad San Sebastián - Investigador
- Facultad de Arquitectura, Arte y Diseño - Investigador
- Sede Santiago - Investigador
- Doctorado en Biología Computacional - Investigador
Person: Researcher
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Raul René Araya Secchi, PhD
- Universidad San Sebastián - Investigador
- Facultad de Ingeniería - Investigador
- Sede Valdivia - Investigador
- Magíster en Biomedicina Molecular - Investigador
- Doctorado en Ingeniería - Investigador
- Doctorado en Biología Computacional - Investigador
- Doctorado en Biología Celular y Biomedicina - Investigador
Person: Researcher
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Carlos Gabriel Cartes Moraga, PhD
- Universidad San Sebastián - Investigador
- Facultad de Ingeniería - Investigador
- Sede Santiago - Investigador
- Doctorado en Biología Computacional - Investigador
Person: Researcher
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FONDECYT R-1261575: Computational Modeling of Viruses for the Study of Their Physical Properties
Poblete Fuentes, S. D. (Investigador(a) Responsable)
01/04/26 → 31/03/30
Project: PROYECTO DE INVESTIGACIÓN
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FONDECYT R-1260530: Developing EEG-Based Brain Clocks for Predicting Neurodegenerative Diseases in Diverse Populations
Prado Gutiérrez, P. (Investigador(a) Responsable), Otero Ferreiro, M. (CoI) & Zañartu, M. (CoI)
01/04/26 → 31/03/29
Project: PROYECTO DE INVESTIGACIÓN
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FONDEF-ID25I10570: CERRANDO LA BRECHA ENTRE TEORÍA Y PRÁCTICA: UN INSTRUMENTO DE VALORACIÓN DEL CAPITAL NATURAL A NIVEL SUBNACIONAL PARA LA TOMA DE DECISIONES DE POLÍTICA PÚBLICA
Pasten Carrasco, R. A. (Director(a)), Roco Fuentes, L. E. (Deputy director), Valenzuela Rivera, L. I. (Investigador(a)), Rodríguez López, L. (Investigador(a)), López Morales, E. J. (Investigador(a)), Fernández Jorquera, F. J. (Investigador(a)), Figueroa Benavides, E. D. L. S. (Investigador(a)), Araos, A. (Investigador(a)) & RIOS WILKS, A. J. (Investigador(a))
02/07/25 → 02/07/27
Project: PROYECTO DE INVESTIGACIÓN APLICADA
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Adaptive Basin Hopping method for first-principles cluster structure prediction
Carmona, O., Arroyo-Valdez, J. A., Muñoz-Castro, A. & Rodríguez-Kessler, P. L., 2026, In: Journal of Nanoparticle Research. 28, 7, 197.Research output: Contribution to journal › Article › peer-review
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A High-Resolution Multifocal RGB Pollen Grain Image Dataset for Deep Learning Computer Vision Tasks from Biobío Region, Chile
Sanhueza Ruiz, I. E., Coelho Caro, P. A., Obregón Rivas, A. M., Staforelli Vivanco, J. P., Viafora, L. A., Troncoso, J. M., Rondanelli-Reyes, M., cariñe, J., Toro, C. A., Jofré, R., Cofré, J., Lamas, I., Salamanca, V. & Muñoz, B., 2026, In: Scientific data. 13, 1Research output: Contribution to journal › Article › peer-review
Open Access -
A negative-hydrated constriction zone is revealed in the active state of the Hv1 channel
Alvear-Arias, J. J., Basaez, D., Carmona, E. M., Galizia, L., Fernandez, M., Peña-Pichicoi, A., Ozu, M., Jorquera, O., Latorre, R., Neely, A., Garate, J. A. & Gonzalez, C., 2026, In: Proceedings of the National Academy of Sciences of the United States of America. 123, 22, e2518376123.Research output: Contribution to journal › Article › peer-review
Open Access
Press/Media
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General artificial intelligence and neurobiology advance toward transformative applications in technology and healthcare
Perez Acle, T. O., Morselli, E., Otero Ferreiro, M. & Varas Godoy, M. A.
13/11/24
1 item of Media coverage
Press/Media
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Eclipse foci, the international consortium seeking to project future pandemics
23/09/24
1 item of Media coverage
Press/Media
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Studies from Computational Biology Lab Describe New Findings in Molecular Science (Protein-Mediated Electroporation in a Cardiac Voltage-Sensing Domain Due to an nsPEF Stimulus)
Perez-Acle, T. O., Villanelo Lizana, F. A., Gárate Chateau, J. A. & Campos Pérez, L. E.
11/08/23
1 item of Media coverage
Press/Media
Equipment
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Espectrofluorímetro Synergy H1
Oyarzun Cayo, P. A. (Manager), Díaz García, V. M. (Manager) & Oyarce Merino, K. A. (Manager)
Equipment/facility: Equipment
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Espectrofotómetro de Absorción Atómica con generador de hidrudos
Ñancucheo Cuevas, I. P. (Manager), Recio Sánchez, G. (Manager) & Oyarzún Cayo, P. A. (Manager)
Equipment/facility: Equipment
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Espectrofotómetro UV-VIS de microplacas y placa Take 3
Oyarzun Cayo, P. A. (Manager), Díaz García, V. M. (Manager) & Oyarce Merino, K. A. (Manager)
Equipment/facility: Equipment